The Accuracy of Intracranial Pressure Non Invasive Measurement Using Transcranial Doppler Versus Invasive Measurement in Pediatric Patients

What this Trial Is About

Increased intracranial pressure (ICP) can cause secondary brain damage, and accurate measurement of ICP is important for managing this condition. The standard method to measure ICP involves invasive placement of intracranial devices, which can carry risks such as bleeding and infection. Researchers are studying non-invasive methods using bedside ultrasound techniques, including Transcranial Doppler (TCD) and measurement of the optic nerve sheath diameter (ONSD), to estimate ICP in children in Pediatric Intensive Care. This research compares the non-invasive ICP measurements obtained by TCD and ONSD with the invasive ICP measurements already in place for pediatric patients. Measurements will be taken within 30 minutes before invasive ICP device placement when possible, and at least twice daily for 48 hours after device placement. Each measurement includes invasive ICP and CPP calculations, TCD flow velocity assessments to estimate non-invasive CPP and ICP, and ONSD measurements, with two independent operators performing ultrasound assessments to evaluate consistency. Participants will have ultrasound assessments during their care, and researchers will collect data on invasive and non-invasive ICP measurements to compare accuracy. The study evaluates inter-operator reliability of ultrasound measurements. The primary outcome focuses on comparing ICP values measured invasively and by TCD within 48 hours after ICP device placement. The study is observational and involves children up to 18 years old who require ICP monitoring, with participation lasting at least two days of twice-daily assessments.

Non Invasive Measurement With Trans Cranial Doppler Versus Invasive Measurement in Pediatric Age