Actively Recruiting
Optical Coherence Tomography Imaging to Visualize Bacteria or Biofilm on Hardware, Bone and Soft Tissue in Open Fracture and Infected Fracture
Led by Dartmouth-Hitchcock Medical Center · Updated on 2025-06-27
40
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
Sponsors
D
Dartmouth-Hitchcock Medical Center
Lead Sponsor
D
Dartmouth College
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are conducting a pilot prospective observational study to examine patients with open or infected fractures. The study evaluates the feasibility and acceptability of optical coherence tomography (OCT), a light-based imaging technique that does not require any drugs or contrast agents. This method aims to visualize bacteria or biofilm on hardware, bone, and soft tissue in these types of fractures. The study includes two groups: patients with high energy open fractures and those with infected open or closed fractures. During the study, participants undergo OCT imaging procedures to assess its practical use and patient acceptance over a 36-month period. Participants will be observed through OCT imaging to collect data on the technique’s usability and patient experience. The research team will measure how feasible and acceptable the OCT imaging is for this patient population. The study is led by Dartmouth-Hitchcock Medical Center and plans to continue through June 2027.
CONDITIONS
Brief Title
OCT in Open Fracture and Infected Fracture
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Open fracture
- Fracture related infection
You will not qualify if you...
- Metatarsal fractures
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 36 months
Participants undergo Optical Coherence Tomography (OCT) imaging to visualize bacteria or biofilm on hardware, bone, and soft tissue in open or infected fractures.
1 to 2 visits depending on fracture type
Duration - Up to 36 months
Participants are observed over time to assess the feasibility and acceptability of OCT imaging in managing open and infected fractures.
Follow-up visits as scheduled based on clinical care
Trial Site Locations
Total: 1 location
1
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States, 03766
Actively Recruiting
Research Team
H
Holly B Symonds
D
Devin S Mullin
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here