Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT04658238

Ocular Microbiome and Immune System in Dry Eyes

Led by Insel Gruppe AG, University Hospital Bern · Updated on 2025-04-01

600

Participants Needed

1

Research Sites

326 weeks

Total Duration

On this page

Sponsors

I

Insel Gruppe AG, University Hospital Bern

Lead Sponsor

S

Stiftung OPOS

Collaborating Sponsor

AI-Summary

What this Trial Is About

The primary objectives of this study are the characterization of the ocular microbiome as well as of the local immune system in participants with and without dry eye disease. Secondary objectives are the identification of differences in the ocular microbiome as well as in the immune system between participants with and without dry eye disease to ultimately find associations between the ocular microbiome and the immune system in dry eye disease.

CONDITIONS

Official Title

Ocular Microbiome and Immune System in Dry Eyes

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Willing to sign informed consent
  • 18 years of age or older
Not Eligible

You will not qualify if you...

  • Not willing or able to sign informed consent
  • Younger than 18 years
  • Recent (3 month) history of use of systemic and/or topical antibiotics
  • Usage of medical eye drops (Lacrycon and other moisturizing eye drops are allowed)
  • Recent (3 month) history of ocular surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Department of Ophthalmology, Inselspital

Bern, Switzerland, 3010

Actively Recruiting

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Research Team

M

Martin Zinkernagel, Prof. Dr. Dr.

CONTACT

D

Denise Zysset, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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