Actively Recruiting
A Study on the Correlation Between Tear Iron Levels and the Severity of Dry Eye Disease.
Led by Shanghai Changzheng Hospital · Updated on 2026-02-10
52
Participants Needed
1
Research Sites
168 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to see if the amount of iron in tears is linked to how severe dry eye disease is. We hope this can lead to a new way to help diagnose and understand dry eye. This is an observational study. We will compare tear samples from people with dry eye to samples from people with healthy eyes. We will measure the iron content in the tears and see if it correlates with standard dry eye test results and symptom scores.
CONDITIONS
Official Title
A Study on the Correlation Between Tear Iron Levels and the Severity of Dry Eye Disease.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 18 and 70 years, inclusive.
- Willing and able to provide written informed consent.
You will not qualify if you...
- History or clinical suspicion of significant systemic conditions such as hematologic diseases, severe infections, malignancies, or chronic liver/kidney failure.
- Use of artificial tears or any topical eye drops within 2 hours before examination.
- Active eye allergy, infection, or severe blepharitis within the past 1 month.
- Use of systemic or topical antibiotics, corticosteroids, NSAIDs, or immunosuppressants within the past 1 month.
- Contact lens use within the past 1 month.
- History of blood transfusion, eye surgery, or major eye injury within the past 6 months.
- Women who are pregnant, breastfeeding, or postmenopausal women on hormone therapy.
- Known allergy to fluorescein sodium.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Changzheng Hospital
Shanghai, China
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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