OPTIMISER Registry A Study on Management and Outcomes in Adults with Acute Myocardial Infarction Treated with PCI or CABG

What this Trial Is About

Researchers are collecting detailed data on patients who have had an acute myocardial infarction AMI, commonly known as a heart attack, and received treatment with percutaneous coronary intervention PCI. This observational study aims to assess procedural success, short- and long-term cardiovascular outcomes, and the performance of different devices and treatment strategies in managing AMI. The study also evaluates device-related complications, antithrombotic treatments, and economic factors related to interventional care for coronary artery disease CAD. Participants who have experienced AMI, including both STEMI and NSTEMI types, and have undergone PCI or coronary artery bypass grafting CABG will have their clinical and procedural data collected both prospectively and retrospectively. Various devices such as balloons, stents, and scaffolds used during PCI will be studied for their effectiveness and safety. The study includes analysis of angiographic and optical coherence tomography OCT findings and investigates predictors of device failure and clinical outcomes over time. Participants will be monitored for major adverse cardiac and cerebrovascular events MACCE, including new heart attacks, strokes, and cardiovascular deaths, with primary outcomes assessed at one year and extended follow-up up to ten years. Data will include hospitalizations, heart failure, arrhythmias, bleeding events, and procedural complications. Clinical outcome data, imaging results, and economic impacts will be recorded to enhance understanding of optimal AMI management and long-term patient prognosis.

OPTIMISER Registry - A Prospective Cohort Study to Describe the OPTIMal Management and Outcomes of PatIents PreSEnting With Acute MyocaRdial Infarction