Actively Recruiting
Oral Health and Wilson's Disease: SOMAWI
Led by Fondation Ophtalmologique Adolphe de Rothschild · Updated on 2025-12-17
150
Participants Needed
3
Research Sites
176 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients with Wilson disease have poorer dental and periodontal health and a have lower oral quality of life than control patients. Patients with a neurological form would also more frequently present limitations in the function of the masticatory apparatus. Systemic treatments for Wilson disease are associated with lesions of the oral mucosa. Analysis of copper level in saliva could testify to the effectiveness of copper depletion in treated patients The main objective is to compare the state of dental health between: patients with Wilson disease in the hepatic form and patients with the neurological form, and a population of controls.
CONDITIONS
Official Title
Oral Health and Wilson's Disease: SOMAWI
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Provide express consent to participate in the study
- Be a member of or beneficiary of a social security scheme
- For cases: Have a diagnosis of Wilson's disease
- For controls: Be undergoing a first routine dental consultation with panoramic imaging, not related to emergency or treatment follow-up
You will not qualify if you...
- Be under legal protection measures
- Be pregnant or breastfeeding
- Have severe psychiatric disorders with behavioral issues
- For cases: Have hepatic or neurological decompensation or have had a liver transplant
- For controls: Have any hepatic or neurological disease
- For controls: Take dietary supplements enriched with copper or zinc, or zinc alone
- For controls: Wear removable prostheses with zinc-enriched prosthetic adhesives (Fixodent ProPlus e)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Hopital Charles Foix
Ivry-sur-Seine, France, 94200
Active, Not Recruiting
2
Hôpital Charles Foix
Ivry-sur-Seine, France, 94200
Active, Not Recruiting
3
Fondation Adolphe de Rothschild
Paris, France, 75019
Actively Recruiting
Research Team
A
Amélie YAVCHITZ
CONTACT
A
Aurélia POUJOIS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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