Study on Tricuspid Regurgitation Progression and Outcomes in Adults With Different Pacemaker Types

What this Trial Is About

Researchers are studying tricuspid regurgitation TR, a common complication after implantation of cardiac implantable electronic devices CIEDs like pacemakers. Severe TR is linked to higher risks of heart failure hospitalization and death, greatly affecting quality of life. This observational study aims to identify factors predicting worsening TR and adverse outcomes in patients with different pacing methods, to guide care for those at high risk. The study reviews patients who had pacemaker implantation between 2015 and 2025, categorized by pacing type right ventricular, conduction system, or biventricular pacing. It analyzes TR progression defined as an increase of at least half a grade. Assessments include 3D echocardiography to understand TR mechanisms, fluoroscopic analysis of pacemaker leads, and evaluation of device-related complications like lead dislodgement or infection, along with heart failure readmissions. Participants data from up to one year of follow-up will be analyzed to measure TR progression and heart failure hospitalizations. The research includes clinical evaluations, imaging studies, and device parameter measurements. This approach helps monitor how pacing modes affect TR and outcomes, aiming to improve management strategies for patients with implanted cardiac devices.

Pacemaker-related Tricuspid Regurgitation Progression and Long-term Outcomes