Actively Recruiting

Age: 18Years +
All Genders
NCT06922526

Pacemaker-related Tricuspid Regurgitation Progression and Long-term Outcomes

Led by Haiyan Wang · Updated on 2025-04-30

200

Participants Needed

1

Research Sites

56 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Tricuspid regurgitation (TR) is a common complication following cardiac implantable electronic device (CIED) implantation, with severe TR being associated with increased rates of heart failure hospitalization and all-cause mortality, significantly impairing patients' quality of life. With technological advancements, physiological pacing modalities have demonstrated superior clinical efficacy and safety profiles compared to conventional pacing methods. This study aims to evaluate predictors of adverse outcomes and TR progression in CIED recipients under different pacing modalities, thereby providing clinical guidance for high-risk patients.

CONDITIONS

Official Title

Pacemaker-related Tricuspid Regurgitation Progression and Long-term Outcomes

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients
  • Patients with an implantable electronic heart device (CIEDs)
  • Patients who underwent pacemaker implantation at Qianfoshan Hospital between 2015 and 2025
Not Eligible

You will not qualify if you...

  • Patients with severe tricuspid regurgitation or prior tricuspid valve surgery or intervention before pacemaker implantation
  • Patients with severe valvular heart disease, congenital heart disease, or arrhythmias
  • Patients with single-chamber pacemakers or poor imaging quality

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The First Affiliated Hospital of Shandong First Medical University

Jinan, China, 250000

Actively Recruiting

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Research Team

H

Haiyan Wang, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

5

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Pacemaker-related Tricuspid Regurgitation Progression and Long-term Outcomes | DecenTrialz