Actively Recruiting

Age: 20Years - 60Years
All Genders
ID06510244

Measuring Pain Perception to the Same Stimulus Using Electroencephalography and Numerical Rate Scale in Adults Aged 20-60 Years

Led by Cleveland Dental Institute · Updated on 2024-07-22

100

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers at the Cleveland Dental Institute are conducting an observational study to assess how patients perceive pain using two non-invasive methods: a numerical rating scale (NRS) and brain wave recordings through electroencephalography (EEG). The study focuses on patients aged 20 to 60 with healthy teeth, no history of dental trauma, and no pulp chamber calcification. The goal is to better understand pain perception by comparing these two measurement approaches. During the study, a cold stimulus (Endo-Ice) will be applied to a healthy upper incisor tooth (#8) to generate a pain response. Participants will rate their pain on a scale from 0 to 10 while the EEG device records their brain activity simultaneously. This data will be analyzed to correlate the subjective pain ratings with objective brain wave patterns. Participants will be involved from January 2024 through December 2024, during which their pain perception will be recorded using both EEG and the numerical scale. Researchers will monitor brain activity and pain ratings concurrently. The study will not involve any treatment but will focus on understanding pain measurement using the non-invasive EEG device and patient self-reporting.

CONDITIONS

Brief Title

Pain Perception Measurement by EEG and NRS

Who Can Participate

Age: 20Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Males and females
  • Age between 20 and 60 years
  • Vital and mature upper front tooth (#8) with adequate coronal structure
  • No history of dentoalveolar trauma
Not Eligible

You will not qualify if you...

  • Chronic periodontitis
  • Vertical root fracture
  • Immature teeth
  • Necrotic teeth
  • Systemic diseases affecting healing
  • Non restorable teeth

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Single session

Participants undergo a nociceptive stimulus where cold is applied to a tooth, and pain perception is recorded alongside brain activity using EEG.

1 visit (in-person)

Trial Site Locations

Total: 1 location

1

Cleveland Dental Institute

Cleveland, Ohio, United States, 44128

Actively Recruiting

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Research Team

U

Ulises Carballosa, Resident

D

Dania Mustafa, Resident

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Published Research Related To This Trial

Resting-state electroencephalography (EEG) biomarkers of chronic neuropathic pain. A systematic review.

Thibaut Mussigmann, Benjamin Bardel, Jean-Pascal Lefaucheur

https://pubmed.ncbi.nlm.nih.gov/35659993

Volume conduction and EEG measurements within the brain: a quantitative approach to the influence of electrical spread on the linear relationship of activity measured at different locations.

J Holsheimer, B W Feenstra

https://pubmed.ncbi.nlm.nih.gov/68872