Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
ID06790641

Pathways to Perinatal Mental Health Equity: Comparing Healthcare System and Healthcare-Community Partnership Approaches to Mood and Anxiety Care During Pregnancy and Postpartum

Led by University of Massachusetts, Worcester · Updated on 2026-04-20

1270

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

U

University of Massachusetts, Worcester

Lead Sponsor

P

Patient-Centered Outcomes Research Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

Mental health conditions during pregnancy and up to one year postpartum affect about one in five individuals, making them a leading cause of death in this period in the United States. This research aims to compare two approaches to improving care for mood and anxiety disorders among pregnant and postpartum individuals. The study involves 32 perinatal care settings across the U.S. to determine whether healthcare systems should invest in a healthcare-only model or a combined healthcare-community partnership model for mental health care during the perinatal period. The study compares two approaches: the healthcare system-focused approach, which integrates screening, assessment, and treatment of mood and anxiety disorders into prenatal and postpartum care through the Program in Support of Moms (PRISM), and the healthcare-community partnership approach, which adds Postpartum Support International (PSI) Peer Support to the PRISM model. The PSI Peer Support pairs individuals with trained volunteers who have experienced and recovered from perinatal mood and anxiety disorders. Both models will be implemented in perinatal care settings, with half assigned to each approach. Participants will be pregnant or postpartum individuals receiving care at the study sites, along with care providers and peer mentors. Researchers will review patient charts to assess treatment initiation and symptom changes in depression and anxiety using recognized scales such as the Edinburgh Postnatal Depression Scale and Patient Health Questionnaire. The study also examines the implementation of mental health screening and support services, professional and mentor experiences, and racial bias and burnout through surveys. The study includes ongoing engagement with advisory councils to gather feedback and identify factors influencing broader adoption of these approaches. The study runs through 2030 with assessments up to 13 months postpartum.

CONDITIONS

Brief Title

Pathways to Perinatal Mental Health Equity

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be 18 years of age or older
  • Have received perinatal care at a study partnering perinatal care setting during the study period
  • Provide verbal consent prior to the focus group or interview
  • Be proficient in English or Spanish (perinatal individuals) or English (care team members and peer mentors)
  • For care team members: be employed in a clinical role at a participating perinatal care setting
  • For peer mentors: have completed PSI training to be a peer mentor
Not Eligible

You will not qualify if you...

  • Individuals who do not meet the inclusion criteria are excluded
  • There are no additional exclusion criteria

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or virtual) to confirm eligibility and provide consent

Outpatient Treatment

Duration - From enrollment through up to 13 months postpartum

Participants receive mental health care through either the Healthcare system approach or the Healthcare-Community Partnership approach, which includes screening, assessment, treatment, and peer support services during pregnancy and postpartum.

Regular visits as part of perinatal care and peer support contacts as offered

Long-term Monitoring

Duration - Up to 13 months postpartum after treatment begins

Participants' mental health symptoms and treatment/support initiation are monitored using surveys and medical chart reviews up to 13 months postpartum to evaluate changes in depression and anxiety symptoms.

Follow-up assessments at multiple time points during postpartum period

Trial Site Locations

Total: 1 location

1

UMass Chan Medical School

Shrewsbury, Massachusetts, United States, 01545

Actively Recruiting

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Research Team

R

Rebekah Getman, PhD

C

Carolyn Friedhoff, M.Bioethics

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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