Actively Recruiting

Age: 18Years +
All Genders
ID07603622

Perioperative Predictive Value of Physical Activity on Short- and Long-term Morbidity and Mortality

Led by Karolinska Institutet · Updated on 2026-05-22

50000

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are examining whether self-reported physical activity before surgery can improve predictions of complications and mortality after surgery. The study focuses on adults undergoing elective non-cardiac surgery and looks at whether physical activity adds value beyond known risk factors like age and other health conditions. The goal is to better understand how physical activity relates to recovery and survival after surgery using data from high-income countries. This observational study collects information such as age, sex, body mass index, existing medical conditions, and physical status before surgery. The key measure is the Metabolic Equivalent of Task Score (MET-score), which reflects patients' physical activity levels reported during preoperative assessment. Researchers will analyze this data using machine learning to see if the MET-score helps predict complications and death better than current methods. Participants will be followed up to monitor mortality at 30, 60, 90, and 365 days after surgery. Additional measures include days alive and at home within 30 and 365 days after surgery, which reflect recovery quality. This study records outcomes to understand risks better and improve patient care, with all data collected during routine assessments and follow-up visits.

CONDITIONS

Brief Title

Perioperative Predictive Value of Physical Activity on Short- and Long-term Morbidity and Mortality

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients (18 years or older) undergoing elective non-cardiac surgery at Karolinska University Hospital Solna or Huddinge
Not Eligible

You will not qualify if you...

  • Patients under 18 years of age
  • Patients undergoing transplant surgery
  • Patients having day surgery
  • Patients having acute or emergency surgery
  • Patients receiving anesthesia monitoring, brachytherapy, or gamma knife interventions
  • Only the first surgery will be included if multiple surgeries occur

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Up to 1 day before surgery

Participants undergo preoperative assessment including recording of physical activity levels and other health parameters.

1 preoperative assessment visit

Monitoring

Duration - 365 days after surgery

Participants are observed for morbidity and mortality outcomes after surgery.

Follow-up assessments at 30, 60, 90, and 365 days after surgery

Trial Site Locations

Total: 1 location

1

Karolinska Institutet

Stockholm, Sweden

Actively Recruiting

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Research Team

M

Max Bell, MD, PhD

A

Arman Valadkhani, MD, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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