Actively Recruiting
Perioperative Predictive Value of Physical Activity on Short- and Long-term Morbidity and Mortality
Led by Karolinska Institutet · Updated on 2026-05-22
50000
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are examining whether self-reported physical activity before surgery can improve predictions of complications and mortality after surgery. The study focuses on adults undergoing elective non-cardiac surgery and looks at whether physical activity adds value beyond known risk factors like age and other health conditions. The goal is to better understand how physical activity relates to recovery and survival after surgery using data from high-income countries. This observational study collects information such as age, sex, body mass index, existing medical conditions, and physical status before surgery. The key measure is the Metabolic Equivalent of Task Score (MET-score), which reflects patients' physical activity levels reported during preoperative assessment. Researchers will analyze this data using machine learning to see if the MET-score helps predict complications and death better than current methods. Participants will be followed up to monitor mortality at 30, 60, 90, and 365 days after surgery. Additional measures include days alive and at home within 30 and 365 days after surgery, which reflect recovery quality. This study records outcomes to understand risks better and improve patient care, with all data collected during routine assessments and follow-up visits.
CONDITIONS
Brief Title
Perioperative Predictive Value of Physical Activity on Short- and Long-term Morbidity and Mortality
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients (18 years or older) undergoing elective non-cardiac surgery at Karolinska University Hospital Solna or Huddinge
You will not qualify if you...
- Patients under 18 years of age
- Patients undergoing transplant surgery
- Patients having day surgery
- Patients having acute or emergency surgery
- Patients receiving anesthesia monitoring, brachytherapy, or gamma knife interventions
- Only the first surgery will be included if multiple surgeries occur
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 1 day before surgery
Participants undergo preoperative assessment including recording of physical activity levels and other health parameters.
1 preoperative assessment visit
Duration - 365 days after surgery
Participants are observed for morbidity and mortality outcomes after surgery.
Follow-up assessments at 30, 60, 90, and 365 days after surgery
Trial Site Locations
Total: 1 location
1
Karolinska Institutet
Stockholm, Sweden
Actively Recruiting
Research Team
M
Max Bell, MD, PhD
A
Arman Valadkhani, MD, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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