Low-Level Laser Therapy to Reduce Fatigue and Improve Quality of Life in Adults with Chronic Fatigue Syndrome

What this Trial Is About

Researchers are investigating whether photobiomodulation therapy, also known as low-level laser therapy, can reduce fatigue and enhance quality of life in adults aged 18 to 60 years with chronic fatigue syndrome CFS. This study aims to compare the effects of active low-level laser therapy against a placebo treatment to see if it significantly improves fatigue levels and other symptoms like pain, functional capacity, sleep, and psychological well-being. Participants will be randomly assigned to receive either the active laser therapy or a sham laser treatment that looks identical but emits no therapeutic laser energy. The therapy targets several muscle groups on both sides of the body, with precise laser application points delivering specific energy doses. Treatments will be given three times per week over an eight-week period, totaling 24 sessions. During the study, participants will undergo assessments at the start and at 3, 6, and 12 months after treatment to measure fatigue, pain, physical function, quality of life, sleep quality, and psychological health. Researchers will monitor safety and any adverse effects throughout the intervention and follow-up periods. The primary outcome focuses on fatigue improvement from baseline to the end of the treatment phase, with additional evaluations extending to six months after completion.

Photobiomodulation in Chronic Fatigue Syndrome