Actively Recruiting
Physical and Cognitive Aging Study in Older Adults
Led by University of Florida · Updated on 2025-05-20
100
Participants Needed
1
Research Sites
130 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Hispanic Americans are the fastest growing older adult group in the United States, disproportionally increasing the risk of an Alzheimer's disease and related dementias diagnosis. Efforts to reduce this risk and mitigate the related cognitive/physical declines are critical. The aim of this study is to assess the feasibility of enrolling older adults into an aging trajectory cohort, while generating preliminary data on associations of physical and cognitive aging trajectories. Our secondary objective is to generate preliminary data on the association of standard measures of physical activity and physical function with cognitive status. This study fits within our longitudinal research goal to reduce dementia incidence by understanding the mechanisms that drive the cognitive-physical aging trajectory.
CONDITIONS
Official Title
Physical and Cognitive Aging Study in Older Adults
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 55-85 years, Hispanic or non-Hispanic, living in the community
- At least 8th grade education
- For Hispanic Americans: self-identify as Hispanic American
- For Hispanic Americans: Spanish is primary language
- No dementia or mild cognitive impairment based on Montreal Cognitive Assessment scores (≥26 for non-Hispanic Whites, ≥25 for Hispanics, ≥24 for non-Hispanic Blacks)
You will not qualify if you...
- Unable to provide informed consent
- Have artificial joints or severe disabilities preventing isokinetic testing
- Sensory loss or motor deficits that prevent participation in study tasks or assessments
- History of major strokes or brain diseases affecting cognition (e.g., Parkinson's, multiple sclerosis, seizure disorders, brain surgery, moderate traumatic brain injury, REM sleep disorder, untreated sleep apnea)
- Unstable or uncontrolled medical conditions such as metastatic cancer, HIV, moderate-severe kidney disease, uncontrolled diabetes or hypertension, severe heart disease, or current cancer diagnosis
- Current or past major psychiatric disorders including schizophrenia, psychosis, bipolar disorder, major depressive episode, or substance abuse within past 6 months
- Use of antipsychotics, sedatives, or medications with significant anticholinergic effects
- Use of prescribed memory-enhancing drugs like Aricept or Namenda
- Participation in cognitive or physical activity training studies in the last 6 months or involvement in other intervention studies at enrollment
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Florida, College of Medicine-Jacksonville
Jacksonville, Florida, United States, 32206
Actively Recruiting
Research Team
S
Stacey Alvarez-Alvarado, PhD, MS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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