Actively Recruiting
Physical and Psychosocial Parameters in Takayasu Arteritis and Behçet's Disease: A Comparative Study With Healthy Controls
Led by ÖZLEM NUR TOK YAMAN · Updated on 2025-12-10
30
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
Sponsors
Ö
ÖZLEM NUR TOK YAMAN
Lead Sponsor
P
Pamukkale University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Systemic vasculitis includes rare diseases that cause inflammation of blood vessels, potentially leading to tissue damage and organ problems. This study compares physical and psychosocial health between people with Takayasu arteritis, Behçet's disease, and healthy individuals. It aims to understand how these diseases affect muscle strength, exercise ability, quality of life, and psychological well-being using a range of clinical and questionnaire assessments. Participants include three groups: those diagnosed with Takayasu arteritis, those with Behçet's disease, and healthy volunteers matched by age and sex. The study does not involve any treatment but focuses on physical and psychosocial evaluations like respiratory and peripheral muscle strength tests, functional exercise tests, and questionnaires on health status and illness perception. All assessments are conducted once at the start of the study. During the study, participants undergo tests such as maximal inspiratory and expiratory pressures, handgrip and limb strength measurements, squat tests, and a six-minute walk test. They also complete validated questionnaires including the Health Assessment Questionnaire, Short Form-36 Health Survey, EuroQol 5-Dimension 5-Level Questionnaire, and Visual Analogue Scale. The research team will analyze differences among groups to guide future rehabilitation and management strategies. Participation involves a single assessment session, with no ongoing treatment or follow-up required.
CONDITIONS
Brief Title
Physical and Psychosocial Parameters in Takayasu Arteritis and Behçet's Disease: A Comparative Study With Healthy Controls
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Diagnosis of Takayasu arteritis according to the American College of Rheumatology classification criteria (for Takayasu arteritis group)
- Diagnosis of Behçet's disease according to the International Study Group criteria (for Behçet's disease group)
- No history of systemic, rheumatologic, or chronic inflammatory disease (for healthy control group)
- Voluntary participation with written informed consent
You will not qualify if you...
- Pregnancy
- Presence of psychiatric disorder or ongoing psychiatric treatment
- Cognitive impairment interfering with participation
- Presence of neurological disease such as hemiplegia, Parkinson's disease, multiple sclerosis, vertigo, epilepsy
- History of any surgical operation within the past year
- Coexisting rheumatic disease other than Takayasu arteritis or Behçet's disease (for patient groups)
- History of rheumatologic or chronic inflammatory disease (for healthy control group)
AI-Screening
AI-Powered Screening
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Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) to confirm eligibility
Duration - Single session at baseline
Participants undergo physical and psychosocial assessments including muscle strength tests, functional capacity tests, and standardized questionnaires.
1 visit (in-person) for assessments and questionnaires
Duration - No active follow-up; observational only after assessments
Participants are observed to understand the multidimensional impact of their condition without any active intervention.
No scheduled visits after baseline assessment
Trial Site Locations
Total: 1 location
1
Pamukkale University
Denizli, Denizli, Turkey (Türkiye)
Actively Recruiting
Research Team
Ö
Özlem Nur Tok Yaman, MSc
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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