Comparing Physical Strength and Quality of Life in Adults with Takayasu Arteritis, Behets Disease, and Healthy Adults

What this Trial Is About

Systemic vasculitis includes rare diseases that cause inflammation of blood vessels, potentially leading to tissue damage and organ problems. This study compares physical and psychosocial health between people with Takayasu arteritis, Behets disease, and healthy individuals. It aims to understand how these diseases affect muscle strength, exercise ability, quality of life, and psychological well-being using a range of clinical and questionnaire assessments. Participants include three groups those diagnosed with Takayasu arteritis, those with Behets disease, and healthy volunteers matched by age and sex. The study does not involve any treatment but focuses on physical and psychosocial evaluations like respiratory and peripheral muscle strength tests, functional exercise tests, and questionnaires on health status and illness perception. All assessments are conducted once at the start of the study. During the study, participants undergo tests such as maximal inspiratory and expiratory pressures, handgrip and limb strength measurements, squat tests, and a six-minute walk test. They also complete validated questionnaires including the Health Assessment Questionnaire, Short Form-36 Health Survey, EuroQol 5-Dimension 5-Level Questionnaire, and Visual Analogue Scale. The research team will analyze differences among groups to guide future rehabilitation and management strategies. Participation involves a single assessment session, with no ongoing treatment or follow-up required.

Physical and Psychosocial Parameters in Takayasu Arteritis and Behçet's Disease: A Comparative Study With Healthy Controls