Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06945484

PILOT for The Precision Exercise Regimen for Cancer Care (PERCC) Study

Led by University of Utah · Updated on 2026-02-03

20

Participants Needed

2

Research Sites

204 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the feasibility of a precision exercise program called the Precision Exercise Regimen for Cancer Care (PERCC) for patients with stage II and stage III Non-Small Cell Lung Cancer (NSCLC) who are undergoing multimodal therapy. This pilot study focuses on whether this exercise program can be successfully implemented through telehealth for lung cancer patients receiving treatments at the University of Utah's Huntsman Cancer Institute. The PERCC program is a home-based exercise intervention supervised virtually. Participants will start exercising at least two weeks before their first neoadjuvant treatment and continue until two months after surgery. The exercises include mobility activities, aerobic, and resistance training performed in various positions such as lying down, sitting, standing, and walking. Each week, participants will have one supervised exercise session via telehealth focusing on resistance exercises, while aerobic exercises will be done individually without supervision. Throughout the study, participants will be monitored from the pre-treatment visit until about two months post-surgery. Researchers will assess recruitment and retention feasibility as the primary outcome, and safety as a secondary outcome during this period. Participants will complete questionnaires and follow the exercise program as prescribed, enabling study staff to evaluate how well the program can be delivered and maintained in this patient population.

CONDITIONS

Brief Title

PILOT for The Precision Exercise Regimen for Cancer Care (PERCC) Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ages 18 and older at time of diagnosis
  • Diagnosed with stage II or stage III non-small cell lung cancer (NSCLC)
  • Receiving neoadjuvant chemotherapy or immunotherapy and surgery
  • Able to follow directions and complete questionnaires in English or Spanish
  • Agree to complete the PERCC exercise intervention
Not Eligible

You will not qualify if you...

  • Morbidly obese (BMI greater than 40 kg/m2) or anorexic (BMI less than 17.5 kg/m2)
  • Abnormalities on screening physical exam that contraindicate exercise participation
  • Alcohol or drug abuse or significant mental or emotional problems interfering with compliance
  • Scheduled to receive only single modality cancer treatment
  • Treatment already started or scheduled to begin within 2 weeks of pre-treatment clinic visit

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

screening and enrollment visit

Treatment

Duration - Starting at least two weeks before neoadjuvant treatment and continuing until two months after surgery

Participants engage in the Precision Exercise Regimen for Cancer Care (PERCC), a virtually supervised home-based exercise program. This includes one supervised exercise session per week via telehealth focusing on resistance exercises, and additional unsupervised aerobic exercise sessions performed individually.

Weekly supervised exercise sessions via telehealth

Trial Site Locations

Total: 2 locations

1

University of Texas Medical Branch at Galveston

Galveston, Texas, United States, 77555

Actively Recruiting

2

Huntsman Cancer Institute

Salt Lake City, Utah, United States, 84112

Actively Recruiting

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Research Team

T

Thomas Varghese, MD, MS, MBA, FACS

C

Cornelia Ulrich, MS, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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