Conservative surgical repair of placenta increta invading into uterine septum: case report.
Omar Yousry Elshorbagy, Mahmoud Ahmed Hamdy
https://pubmed.ncbi.nlm.nih.gov/39551821Actively Recruiting
Led by Alexandria University · Updated on 2025-02-12
120
Participants Needed
1
Research Sites
14 weeks
Total Duration
Researchers are studying women with placenta accreta spectrum (PAS) who have undergone uterine conservation during cesarean delivery. The study aims to evaluate the immediate success of preserving the uterus, including measuring blood loss and transfusion needs, and to follow patients over time to assess menstrual return, uterine abnormalities, and related symptoms. This research focuses on short- and intermediate-term outcomes after cesarean section for PAS to better understand the procedure's effects. The treatment involves surgically delivering the fetus by incising the uterus above the placenta bulge, followed by administration of Carbetocin to aid uterine contraction. The uterine wall defect is repaired with running sutures, and if excessive bleeding occurs, additional procedures like internal iliac artery ligation may be used. Three months after delivery, all patients receive ultrasound assessments, and symptomatic patients or those with abnormal ultrasound findings undergo outpatient hysteroscopy to evaluate uterine health. Participants provide detailed medical and obstetric history, undergo physical exams and laboratory tests, and receive sonographic evaluations before surgery. During and after surgery, researchers record operative details, blood loss, transfusions, and complications. Follow-up includes monitoring return of menses, menstrual abnormalities, pelvic pain, uterine defects like isthmocele, and intrauterine adhesions between 2 weeks and 6 months post-surgery. Outcomes such as blood loss, surgical time, and hospital stay are also measured, with data collection extending up to 10 days post-operation and follow-up continuing for several months.
CONDITIONS
Placenta Accreta Spectrum Outcome After Uterine Conservation
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Intraoperative and immediate postoperative period up to 10 days
Participants undergo cesarean section with uterine conservation involving closure of the uterine wall defect and associated surgical procedures.
Hospital stay with daily monitoring until discharge
Duration - From 3 to 6 months after surgery
Participants receive ultrasound evaluations at delivery and at 3 months post-surgery to assess uterine wall and placental site, with outpatient hysteroscopy if symptomatic or abnormal ultrasound findings occur.
1 ultrasound visit at 3 months and outpatient hysteroscopy if needed
Total: 1 location
1
Faculty of Medicine
Alexandria, Alexandria Governorate, Egypt, 21131
Actively Recruiting
O
Omar Y Elshorbagy, As.lec
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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Omar Yousry Elshorbagy, Mahmoud Ahmed Hamdy
https://pubmed.ncbi.nlm.nih.gov/39551821