Postprandial Triglyceride Impact on Coronary Atherosclerosis in Non-Diabetic Patients at Sohag University Hospital
Led by Fatma Madhy Eissa · Updated on 2024-07-15
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What this Trial Is About
Coronary artery disease (CAD) is a leading cause of death worldwide, caused by the buildup of fats and inflammatory cells in the arteries, a process called atherosclerosis. This condition is closely linked to lipid levels in the blood, including cholesterol and triglycerides. This research focuses on how the rise in triglyceride levels after eating, called postprandial triglycerides, may influence the development of coronary atherosclerosis in patients without diabetes.
The study observes patients with different coronary artery conditions based on angiography results and postprandial triglyceride levels. Participants are placed into groups: those with normal coronary arteries and triglycerides, those with abnormal arteries and high triglycerides above 200 mg/dL, and those with abnormal arteries but normal triglycerides. The severity of coronary artery disease in affected patients is further classified by a scoring system. The study uses diagnostic tests to measure the impact of postprandial triglycerides on coronary atherosclerosis.
During the seven-month study period, researchers monitor postprandial triglyceride levels and coronary artery conditions using laboratory tests, ECG, and angiography. They assess the relationship between triglyceride levels after meals and the severity of coronary artery disease. Participants undergo regular evaluations to track these measurements, helping researchers understand the role of triglycerides in coronary atherosclerosis progression in non-diabetic patients.
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Brief Title
Postprandial Triglyceride Impact on Coronary Atherosclerosis in Non-Diabetic Patient in Sohag University Hospital
Who Can Participate
All Genders
Eligibility Criteria
You may qualify if you...
Diagnosis of coronary artery disease based on coronary angiography, laboratory tests, and ECG evidence
You will not qualify if you...
Presence of liver disorders
Presence of kidney disorders
Presence of thyroid diseases
Diagnosis of diabetes
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Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Diagnostic Evaluation
Duration - Single assessment
Participants undergo diagnostic tests to assess postprandial triglyceride levels and coronary artery status.
1 visit (in-person)
Long-term Monitoring
Duration - 7 months
Participants are monitored over 7 months to observe the impact of postprandial triglyceride levels on coronary atherosclerosis.
2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.