Actively Recruiting
Carotid Atherosclerosis in Predicting Coronary Artery Disease
Led by Shanghai Zhongshan Hospital · Updated on 2024-02-12
1000
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research investigates the link between different patterns of carotid artery atherosclerosis and the presence, type, and severity of coronary artery disease in patients experiencing chest tightness or chest pain. The study focuses on how features like carotid plaque burden and lipid necrotic core relate to coronary artery narrowing. Researchers aim to better understand how carotid artery conditions may predict coronary artery disease severity. Participants will undergo carotid artery ultrasound imaging before receiving coronary angiography, a procedure to assess coronary artery disease severity. The study observes patients with and without carotid atherosclerosis to explore the relationship between carotid and coronary artery conditions. This is an observational study without intervention groups or treatments. During the study, patients will be evaluated through carotid ultrasounds and coronary angiography. Researchers will monitor major adverse cardiovascular events (MACE) over two years following angiography to assess outcomes. The study spans several years, allowing long-term observation of cardiovascular risks and disease progression in participants aged 14 to 90 years.
CONDITIONS
Brief Title
Carotid Atherosclerosis in Predicting Coronary Artery Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients scheduled to receive carotid ultrasound and coronary angiography
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 1 week
Participants undergo carotid ultrasound and coronary angiography to assess carotid atherosclerosis and coronary artery disease.
1 to 2 visits depending on scheduled procedures
Duration - 2 years
Participants are monitored for major adverse cardiovascular events (MACE) for two years after angiography.
Periodic monitoring visits over 2 years
Trial Site Locations
Total: 1 location
1
180 Fenglin Road
Shanghai, China, 200032
Actively Recruiting
Research Team
D
Danbo Lu, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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