Actively Recruiting
Study of Carotid Atherosclerosis to Predict Coronary Artery Disease in Patients Aged 14 to 90
Led by Shanghai Zhongshan Hospital · Updated on 2024-02-12
1000
Participants Needed
1
Research Sites
104 weeks
Total Duration
AI-Summary
What this Trial Is About
This research investigates the link between different patterns of carotid artery atherosclerosis and the presence, type, and severity of coronary artery disease in patients experiencing chest tightness or chest pain. The study focuses on how features like carotid plaque burden and lipid necrotic core relate to coronary artery narrowing. Researchers aim to better understand how carotid artery conditions may predict coronary artery disease severity. Participants will undergo carotid artery ultrasound imaging before receiving coronary angiography, a procedure to assess coronary artery disease severity. The study observes patients with and without carotid atherosclerosis to explore the relationship between carotid and coronary artery conditions. This is an observational study without intervention groups or treatments. During the study, patients will be evaluated through carotid ultrasounds and coronary angiography. Researchers will monitor major adverse cardiovascular events MACE over two years following angiography to assess outcomes. The study spans several years, allowing long-term observation of cardiovascular risks and disease progression in participants aged 14 to 90 years.
CONDITIONS
Brief Title
Carotid Atherosclerosis in Predicting Coronary Artery Disease
Research Team
D
Danbo Lu, PhD
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