Accuracy of Platelet-Lymphocyte and Platelet-Neutrophil Ratios in Early Detection of Trauma-Induced Blood Clotting Problems

What this Trial Is About

Trauma is a major cause of injury and death worldwide, often leading to significant health challenges. This research aims to evaluate how well the platelet-lymphocyte ratio PLR and platelet-neutrophil ratio PNR predict early trauma-induced coagulopathy ETIC in patients arriving at the emergency department ED within six hours of injury. These ratios reflect the balance between inflammation and immune response, which may help identify patients at risk early in their hospital stay. The study observes trauma patients who come to the ED and have blood tests ordered by their physician, specifically coagulation profiles. It focuses on measuring the PLR and PNR values upon admission, without administering any new treatments or interventions. The goal is to see how these markers predict outcomes such as the need for blood transfusions, prolonged ventilatory support, surgeries, and length of hospital stay during their admission. Participants will be monitored during their hospital stay, with researchers assessing laboratory results and clinical events such as transfusions, surgeries, and intensive care days. The main outcome is the accuracy of PLR and PNR in detecting ETIC within 24 hours. Secondary outcomes include comparing predictive values for transfusion needs, ventilatory support duration, emergent surgeries, and hospital stay length up to 30 days. The study is observational and does not involve additional treatments or procedures beyond usual care.

Predictive Accuracy of PLR and PNR in Detecting ETIC