Actively Recruiting
LiveWellLung: A Prehabilitation Program to Promote Resiliency and Operative Success for Adults Receiving Lung Cancer Surgery with Biospecimen Collection
Led by Ohio State University Comprehensive Cancer Center · Updated on 2026-05-26
30
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical trial evaluates two different physical therapy and relaxation intervention programs designed to promote resiliency and improve surgical outcomes for adults undergoing lung cancer surgery. These prehabilitation programs aim to improve physical performance, mood, and recovery after surgery for potentially resectable non-small cell lung cancer. Researchers are studying how these interventions may support emotional and physical recovery, shorten hospital stays, and possibly extend survival. The trial offers two intervention options: Arm I (ROAR-LCS) includes in-person and virtual physical therapy sessions with cardiovascular warm-up, core exercises, and resistance training along with guided progressive muscle relaxation exercises. Patients receive exercise equipment for home use and complete 6-8 sessions before surgery and a total of 12 sessions over 3-4 months. Arm II (BeFitMe) provides access to a smartphone app, an Apple watch, and an exercise flip book for 9 months, with assigned self-guided exercises lasting at least 3 minutes, motivational texts, and activity tracking. Both groups undergo blood sample collection during the study. Participants are involved in regular therapy sessions, exercise routines, and relaxation practices, with monitoring of adherence and retention as primary outcomes. Blood samples are collected to explore biomarkers related to treatment toxicity and tumor response. After completing the intervention, participants are followed for 1 and 2 years to assess long-term outcomes. The study measures feasibility and participant engagement alongside clinical results to better understand how these programs support recovery after lung cancer surgery.
CONDITIONS
Brief Title
Prehabilitation Physical Therapy and Relaxation Intervention Program to Promote Resiliency and Operative Success Among Adults Receiving Lung Cancer Surgery, ROAR-LCS Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Diagnosed with potentially resectable non small cell lung cancer (NSCLC) stage IB to IIIB
- Plan to receive surgery following neoadjuvant systemic therapy at the Ohio State University Comprehensive Cancer Center Thoracic Oncology Clinic
- At least 6 weeks out from surgery date
- Willing to participate and adhere to the study intervention program
- Able to understand and willing to sign informed consent
You will not qualify if you...
- Prisoners are not allowed to participate
- No exclusion based on performance status, lab values, or prior cancer diagnoses
- Patients currently enrolled in another therapeutic clinical trial will be excluded unless approved by the local site principal investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 3 to 4 months for ROAR-LCS; 9 months for BeFitMe
Participants engage in either the ROAR-LCS program with physical therapy sessions and relaxation exercises or the BeFitMe program with app-guided exercises and motivational support while undergoing blood sample collection.
6 to 8 in-person physical therapy sessions before surgery and additional virtual sessions for ROAR-LCS; daily app use and motivational texts for BeFitMe
Duration - Up to 2 years
Participants are followed up for assessment of adherence, retention, and clinical outcomes at 1 and 2 years after intervention completion.
2 visits (in-person) at 1 and 2 years post intervention
Trial Site Locations
Total: 1 location
1
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States, 43210
Actively Recruiting
Research Team
T
The Ohio State University Comprehensive Cancer Center
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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