Perioperative Acute Kidney Injury: An Under-Recognized Problem.
Melanie Meersch, Christoph Schmidt, Alexander Zarbock
https://pubmed.ncbi.nlm.nih.gov/28787339Actively Recruiting
Age: 18Years - 80Years
All Genders
ID06857630
The Association Between Preoperative Hemoglobin and Acute Kidney Injury in Emergency Surgery: A Prospective Observational Study
Led by Samsun University · Updated on 2026-03-17
420
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying how hemoglobin levels before emergency surgery affect the chance of developing acute kidney injury (AKI) afterward. While anemia is linked to serious organ problems like coronary artery disease, the impact of blood transfusions or other ways to raise hemoglobin on patient outcomes remains unclear. This study aims to clarify the relationship between preoperative hemoglobin and AKI after adjusting for known risk factors. This prospective observational study involves patients having emergency non-cardiac surgery. Participants will be divided into two groups: those who develop postoperative AKI and those who do not. Researchers will assess kidney injury using established criteria based on blood and urine tests. Data collected will include patient demographics, blood counts, biochemistry, fluid and blood replacement, surgery details, and the severity of any kidney injury. Participants will be monitored closely during and after surgery to record kidney function changes and hospital stay length. The primary outcome is the occurrence of acute kidney injury within 72 hours after surgery. Secondary outcomes include the total days spent in the hospital within one month. This careful observation will help understand how pre-surgery hemoglobin levels relate to kidney health after emergency operations.
CONDITIONS
Brief Title
Preoperative Hemoglobin and Acute Kidney Injury in Emergency Surgery
Who Can Participate
Age: 18Years - 80Years
All Genders
Eligibility Criteria
You may qualify if you...
- Patients undergoing emergency non-cardiac surgery
- Age between 18 and 80 years
- Ability to provide informed consent and agree to participate in the study
You will not qualify if you...
- Known renal failure
- Need for reoperation within 48 hours after surgery
- Death within 48 hours postoperatively
- Known hematological disease
- History of kidney transplantation
- Urgent surgery planned for urinary system-related diseases
- Declined to participate in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Diagnostic Evaluation
Duration - Surgery day
Participants undergo emergency non-cardiac surgery and preoperative hemoglobin levels are recorded.
1 visit (in-person)
Monitoring
Duration - Up to 72 hours post-surgery
Participants are observed for the development of postoperative acute kidney injury (AKI) and recovery during the hospital stay.
Daily visits for up to 3 days
Long-term Monitoring
Duration - Up to 1 month
Participants' hospital stay and recovery are monitored for up to 1 month after surgery.
Additional visits as part of hospital stay
Trial Site Locations
Total: 1 location
1
Özgür Kömürcü
Samsun, Turkey (Türkiye), 55200
Actively Recruiting
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Research Team
Ö
özgür kömürcü, 1
Ö
özgür kömürcü, 2
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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