Actively Recruiting
Preterm Immune System Development and Response to Immunization
Led by Maastricht University Medical Center · Updated on 2024-03-20
145
Participants Needed
7
Research Sites
185 weeks
Total Duration
On this page
Sponsors
M
Maastricht University Medical Center
Lead Sponsor
M
Medical Center Haaglanden
Collaborating Sponsor
AI-Summary
What this Trial Is About
In this study the response to vaccination and development of the immune system in very preterm infants upon the current vaccination schedule will be compared to healthy term infants.
CONDITIONS
Official Title
Preterm Immune System Development and Response to Immunization
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Preterm infant born at gestational age less than 32 weeks (mothers may or may not have received Tdap vaccination during pregnancy)
- Parents or guardians must have sufficient understanding of the Dutch language
- Healthy full-term infant whose mother received a Tdap vaccination during pregnancy
- Mother of preterm or healthy full-term infant who are participating in the study
You will not qualify if you...
- Parents or guardians of the infant are not able or willing to provide informed consent
- Infant with congenital anomalies likely to cause adverse effects after immunization, such as hemodynamically significant congenital heart defect
- Infant with a possible HIV infection or immunodeficiency
- Maternal use of immunosuppressive drugs during pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 7 locations
1
Amphia Hospital
Breda, Netherlands, 4819 EV
Actively Recruiting
2
reinier de Graaff Group
Delft, Netherlands, 2625 AD
Actively Recruiting
3
Albert Schweitzer Hospital
Dordrecht, Netherlands, 3318 AT
Actively Recruiting
4
Erasmus MC
Rotterdam, Netherlands, 3015 GD
Actively Recruiting
5
Franciscus Gasthuis
Rotterdam, Netherlands, 3045 PM
Actively Recruiting
6
Maasstad Hospital
Rotterdam, Netherlands, 3079 DZ
Actively Recruiting
7
Maxima Medical Center
Veldhoven, Netherlands, 5504 DB
Actively Recruiting
Research Team
G
Gertjan Driessen, Prof MD PhD
CONTACT
J
Jantien Bolt-Wieringa, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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