Actively Recruiting
Prevalence of Gag Reflex in Healthy Persons and Across Different Patient Groups and Its Relevance in Dysphagia Screening
Led by University of Giessen · Updated on 2024-07-08
700
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the presence of the gag reflex in healthy young and older adults, as well as in patients with neurological diseases such as acute stroke, Parkinson's Disease, Myasthenia gravis, Multiple Sclerosis, and in geriatric patients. The study examines how often the gag reflex occurs across these groups and its importance in screening for swallowing difficulties (dysphagia). It also considers factors like patient cooperation and oral anatomy that may affect gag reflex testing. Participants undergo a diagnostic test where the gag reflex is stimulated and observed in different parts of the mouth, including the tongue, soft palate (velum), and pharyngeal wall. The Mallampati score, a measure related to mouth anatomy, is also assessed to understand how feasible the gag reflex test is in people with varying oral structures. Each participant is tested once by a trained examiner. During the study visit, participants receive the gag reflex test and the Mallampati score assessment. Researchers record the presence or absence of the gag reflex and the reactions in the tested areas. This data helps to evaluate how common the gag reflex is in different groups and how useful it might be for detecting swallowing problems. The main measurement is the prevalence of the gag reflex at baseline.
CONDITIONS
Brief Title
Prevalence of Gag Reflex in Healthy Persons and Across Different Patient Groups and Its Relevance in Dysphagia Screening
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Provided informed consent
- Age 18 years or older
You will not qualify if you...
- Healthy participants with neurological diseases
- Healthy participants with pre-diagnosed dysphagia
- Healthy participants with percutaneous endoscopic gastrostomy (PEG) tube
- Healthy participants with head and neck tumours
- Healthy participants who had chemo- and/or radiotherapy in the head and neck area
- Healthy participants with reflux disease
- Healthy participants with chronic obstructive pulmonary disease (COPD)
- Healthy participants with previous surgeries on the cervical spine or thyroid gland
- Healthy participants with vocal cord paresis
- Geriatric patients with neurologic diseases
- Stroke patients with head and neck tumours
- Stroke patients who had chemo- and/or radiotherapy in the head and neck area
- Stroke patients with reflux disease
- Stroke patients with COPD
- Stroke patients with previous surgeries on the cervical spine or thyroid gland
- Stroke patients with vocal cord paresis
- Neurologic patients without stroke with head and neck tumours (except intracranial tumors)
- Neurologic patients without stroke who had chemo- and/or radiotherapy in the head and neck area
- Neurologic patients without stroke with reflux disease
- Neurologic patients without stroke with COPD
- Neurologic patients without stroke with previous surgeries on the cervical spine or thyroid gland
- Neurologic patients without stroke with vocal cord paresis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single visit
Participants undergo testing of gag reflex in different oral areas and assessment of the Mallampati score to evaluate the feasibility of the gag reflex test.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
University Hospital Giessen and Marburg
Giessen, Hesse, Germany, 35392
Actively Recruiting
Research Team
S
Samra Hamzic, M.A.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
7
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