Actively Recruiting

Age: 2Years +
All Genders
Healthy Volunteers
NCT04806620

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

Led by Brain Inflammation Collaborative · Updated on 2026-01-22

10000

Participants Needed

1

Research Sites

390 weeks

Total Duration

On this page

Sponsors

B

Brain Inflammation Collaborative

Lead Sponsor

S

Solve ME/CFS Initiative

Collaborating Sponsor

AI-Summary

What this Trial Is About

The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related neuroinflammatory conditions. Participants in the United States aged 2 years and older will provide self-reported health data, biometrics, and symptom diaries through the MyDataHelps™ app (branded as unhide® for this study). The goal is to create comprehensive longitudinal profiles to facilitate research into disease subtypes, causes, diagnostics, and potential treatments, as well as to identify potential participants for future optional studies. "Healthy" individuals without brain inflammation are also eligible to participate. The digital health research platform used in this study was originally developed and designed by Solve M.E and was called SolveTogether. The Brain Inflammation Collaborative (BIC) expanded upon Solve M.E.'s work to include related diagnoses, pediatric participants, enhance symptom tracking, and more. BIC and Solve M.E. combined Solve Together and unhide®, to create The unhide® Solve Together Unified Platform in 2025.

CONDITIONS

Official Title

Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

Who Can Participate

Age: 2Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Be 2 years of age or older
  • Currently live in the United States
  • Have consistent internet access and a cell phone, tablet, or PC
  • Be able to participate in English
  • Be willing to share symptom and health data through the platform
  • Self-identify or be diagnosed with infection-associated chronic conditions such as Long COVID, chronic Lyme, myalgic encephalomyelitis (ME/CFS), or post-acute neuropsychiatric syndrome (PANS/PANDAS)
  • Self-identify or be diagnosed with neuroimmune, developmental, autonomic, or neurological conditions like migraines, dysautonomia, POTS, multiple sclerosis, or autism spectrum disorder
  • Self-identify or be diagnosed with autoimmune diseases such as Lupus, Sjogren's Disease, rheumatoid arthritis, myasthenia gravis, ankylosing spondylitis, or related autoimmune conditions
  • Self-identify or be diagnosed with inflammatory gastrointestinal conditions such as Crohn's Disease, Celiac Disease, or ulcerative colitis
  • Self-identify or be diagnosed with behavioral and mood disorders such as anxiety, depression, bipolar disorder, PTSD, eating disorders, or OCD
  • Healthy individuals without brain inflammation, including unaffected family members or household members
Not Eligible

You will not qualify if you...

  • Living outside the United States
  • Being a ward of the state
  • Having decisional impairment

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Brain Inflammation Collaborative

Delafield, Wisconsin, United States, 53018

Actively Recruiting

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Research Team

M

Megan L Fitzgerald, PhD

CONTACT

C

Christina Moon

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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