Actively Recruiting

Age: 18Years +
All Genders
ID07016685

Prognostic Factors for 90-day Mortality in Patients Undergoing Veno-venous Extracorporeal Membrane Oxygenation for Emergency Thoracic Surgery

Led by Centre Hospitalier Universitaire, Amiens · Updated on 2025-06-13

380

Participants Needed

1

Research Sites

21 weeks

Total Duration

On this page

Sponsors

C

Centre Hospitalier Universitaire, Amiens

Lead Sponsor

C

Centre Hospitalier Universitaire Dijon

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the use of veno-venous extracorporeal membrane oxygenation (VV-ECMO) in patients undergoing emergency thoracic surgery. This observational study aims to understand clinical outcomes and identify factors that affect prognosis in this high-risk group by comparing them to patients who received VV-ECMO for medical respiratory failure. Data is collected from two French academic centers, focusing on 90-day mortality and complications. The study compares two groups: patients receiving VV-ECMO during or after emergency thoracic surgery and those receiving VV-ECMO for medical respiratory failure. It is a retrospective, multicenter study that collects clinical data to assess differences in outcomes between these groups, including mortality and postoperative complications. The study does not involve experimental treatments but analyzes existing medical records. Participants will have their clinical data reviewed, including 90-day all-cause mortality and rates of complications following surgery. Researchers will study differences in mortality between oncologic and non-oncologic thoracic surgeries. The study spans from June 2025 to April 2026, focusing on gathering and analyzing retrospective data without requiring active treatment or intervention from participants during this period.

CONDITIONS

Brief Title

Prognosis of Veno-Venous Extracorporeal Membrane Oxygenation in Emergency Thoracic Surgery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults 18 years or older
  • VV-ECMO started during or after emergency thoracic surgery
  • No opposition to use of personal medical data
Not Eligible

You will not qualify if you...

  • Pregnant women
  • Patients on veno-arterial ECMO
  • Persons under legal protection or guardianship status prohibited from consent

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Monitoring

Duration - 90 days

Participants who undergo emergency thoracic surgery and VV-ECMO are observed for outcomes including mortality and complications.

Regular assessments during hospital stay and follow-up visits up to 90 days

Trial Site Locations

Total: 1 location

1

CHRU Amiens

Amiens, France, 80480

Actively Recruiting

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Research Team

C

Christophe Beyls, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Published Research Related To This Trial

Perioperative Veno-Venous Extracorporeal Membrane Oxygenation in Non-Elective Thoracic Surgery: A Propensity-Matched Bicentric Comparison With Medical Indication.

Christophe Beyls, Quintana Soulier-Zaninka, Olivier Georges...

https://pubmed.ncbi.nlm.nih.gov/41134639