Actively Recruiting

Age: 18Years +
All Genders
ID07184463

Chronic Pain After Thoracic Surgery: A Comparative Study of Pain Reduction After Pulmonary Resection by RATS-TT, RATS-OTC, and Hybrid RATS

Led by Centre hospitalier de l'Université de Montréal (CHUM) · Updated on 2026-02-23

120

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to compare chronic pain outcomes following different robotic-assisted thoracic surgery (RATS) techniques used for pulmonary resections in patients with lung tumors. These surgeries are important for treating lung neoplasms, with approaches tailored to tumor size and location. Minimally invasive surgeries like video-assisted thoracic surgery (VATS) have reduced acute pain but chronic pain remains a concern. The study evaluates three RATS methods: the transthoracic approach (RATS-TT), the "out of cage" technique (RATS-OTC) that avoids intercostal nerve injury, and a hybrid method (RATS-TTH) used at CHUM. Participants will have pulmonary resection surgery using one of the three RATS techniques. RATS-TT uses intercostal trocars for instruments and specimen removal, RATS-OTC avoids intercostal access by using subcostal or subxiphoid ports, and RATS-TTH combines intercostal instrument access with out-of-cage specimen extraction to reduce nerve trauma. The study observes pain at 3 and 6 months post-surgery to assess chronic pain incidence. These approaches are compared to understand their effects on persistent pain after surgery. Participants will be followed up at 3 and 6 months after surgery to assess persistent postoperative pain, including chest pain at rest or with coughing. Pain will be evaluated by patient response, and additional assessments include neuropathic pain components, overall recovery, analgesic use, opioid consumption, hospital stay length, residual pain intensity, and presence of dysesthesia. The study collects data on these outcomes to better understand long-term pain following different surgical techniques for lung tumor removal.

CONDITIONS

Brief Title

A Study of Pain Reduction After Pulmonary Resection by RATS-TT, RATS-OTC, and Hybrid RATS.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 years and older
  • American Society of Anesthesiologists (ASA) score 1-3
Not Eligible

You will not qualify if you...

  • Language barrier, psychiatric, physical or mental condition making pain assessment impossible despite prior education
  • Patient refusal to participate
  • Patients reoperated by VATS or thoracotomy in the postoperative period due to complications

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surgery and Immediate Post-operative Care

Duration - Up to 2 weeks or until discharge

Participants undergo pulmonary resection surgery using one of three robotic-assisted thoracic surgery approaches and receive immediate post-operative care during hospitalization.

Hospital stay with daily assessments until discharge

Post-operative Follow-up

Duration - 6 months

Participants are assessed for chronic pain and recovery outcomes at 3 and 6 months after surgery.

2 visits (at 3 months and 6 months post-surgery)

Trial Site Locations

Total: 1 location

1

Centre Hospitalier de l'Université de Montreal

Montreal, Quebec, Canada, H2X 3E4

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Research Team

A

Alex Moore, MD

J

Julie Desroches, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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