Pilot Study on Inhaled Nitric Oxide Combined With Prone Positioning to Treat ARDS in Adults Aged 18 to 80

What this Trial Is About

Researchers are evaluating the impact of combining inhaled nitric oxide with prone positioning ventilation on patients with moderate to severe Acute Respiratory Distress Syndrome ARDS who are receiving mechanical ventilation. This pilot study aims to assess the effectiveness of this combination approach under Electrical Impedance Tomography EIT monitoring to better understand its effects on lung function in ARDS patients. The study involves treating participants with a combination of inhaled nitric oxide and prone position ventilation. This is an interventional procedure designed to improve respiratory outcomes. Participants will be monitored using EIT during the treatment to observe intratidal gas distribution over a 12-hour period. During the study, participants will undergo continuous monitoring of their lung function and gas distribution for 12 hours. Researchers will evaluate the primary outcome measure of intratidal gas distribution to determine treatment effects. The study includes adult patients aged 18 to 80 years and excludes those with certain medical conditions or complications. Participation involves following the treatment and monitoring procedures as outlined by the medical team, with a study period lasting until the end date in 2025.

A Pilot Study of the Effect of the Combination of Inhaled Nitric Oxide and Prone Position Under EIT Monitoring on Efficacy in Patients with ARDS