Actively Recruiting
Prospective Clinical Registry of Acute Treatment and Long-term Assessment of Children Meningitis
Led by Hospital Israelita Albert Einstein · Updated on 2026-05-05
600
Participants Needed
1
Research Sites
44 weeks
Total Duration
On this page
Sponsors
H
Hospital Israelita Albert Einstein
Lead Sponsor
M
Ministry of Health, Brazil
Collaborating Sponsor
AI-Summary
What this Trial Is About
Prospective, multicenter, observational clinical registry of pediatric patients with acute infectious meningitis across approximately 20 public and private hospitals in Brazil. The study will include children under 18 years of age with suspected acute infectious meningitis. Data will be collected during hospitalization and post-discharge to evaluate clinical management, treatment and short and long-term outcomes. The study aims to generate real-world evidence on current practices and outcomes to support improvements in national care protocols.
CONDITIONS
Official Title
Prospective Clinical Registry of Acute Treatment and Long-term Assessment of Children Meningitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children under 18 years with fever (axillary temperature ≥37.8°C) plus two or more symptoms such as severe headache, vomiting, altered consciousness (confusion, drowsiness, irritability), photophobia, or seizures
- Children with fever and at least one meningeal irritation sign: neck stiffness, Kernig's sign, or Brudzinski's sign
- Children with sudden fever and petechial skin rash or hemorrhagic suffusions
- For children younger than 2 years, fever with irritability, persistent crying, somnolence, or bulging fontanelle also qualify
You will not qualify if you...
- Refusal to provide consent for study participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hospital Israelita Albert Einstein
São Paulo, São Paulo, Brazil, 05653-000
Actively Recruiting
Research Team
A
Anna M Gomes
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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