Actively Recruiting
Acute Treatment and Long-term Assessment of Adult Infectious Meningitis
Led by Hospital Israelita Albert Einstein · Updated on 2026-05-07
624
Participants Needed
3
Research Sites
44 weeks
Total Duration
On this page
Sponsors
H
Hospital Israelita Albert Einstein
Lead Sponsor
M
Ministry of Health, Brazil
Collaborating Sponsor
AI-Summary
What this Trial Is About
Prospective, multicenter, observational clinical registry of adult patients with acute infectious meningitis across approximately 30 public and private hospitals in Brazil. The study will include adults, 18 years old and older, with suspected acute infectious meningitis. Data will be collected during hospitalization and post-discharge to evaluate clinical management, treatment and short and long-term outcomes. The study aims to generate real-world evidence on current practices and outcomes to support improvements in national care protocols.
CONDITIONS
Official Title
Acute Treatment and Long-term Assessment of Adult Infectious Meningitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older
- Fever (axillary temperature e37.86C) followed by two or more of the following symptoms: severe headache, vomiting, altered consciousness (confusion, drowsiness, or irritability), photophobia (increased sensitivity to light), presence of seizures
- Fever accompanied by at least one meningeal irritation sign such as neck stiffness, Kernig's sign, or Brudzinski's sign
- Sudden onset of fever and appearance of petechial skin rash or hemorrhagic suffusions
You will not qualify if you...
- Refusal to provide consent for study participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Hospital São Vicente de Paulo
Passo Fundo, Rio Grande do Sul, Brazil, 99010-080
Actively Recruiting
2
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto - USP
Ribeirão Preto, São Paulo, Brazil, 14051-140
Actively Recruiting
3
Hospital Santa Marcelina
São Paulo, São Paulo, Brazil, 08270-070
Actively Recruiting
Research Team
A
Anna M Gomes, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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