Actively Recruiting
Central Nervous System Infections in Denmark
Led by Aalborg University Hospital · Updated on 2024-05-16
1900
Participants Needed
8
Research Sites
782 weeks
Total Duration
On this page
Sponsors
A
Aalborg University Hospital
Lead Sponsor
D
Danish Study Group of Infections of the Brain
Collaborating Sponsor
AI-Summary
What this Trial Is About
The Danish Study Group of Infections of the Brain is a collaboration between all departments of infectious diseases in Denmark. The investigators aim to monitor epidemiological trends in central nervous system (CNS) infections by a prospective registration of clinical characteristics and outcome of all adult (\>17 years of age) patients with community-acquired CNS infections diagnosed and/or treated at departments of infectious diseases in Denmark since 1st of January 2015.
CONDITIONS
Official Title
Central Nervous System Infections in Denmark
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults older than 17 years of age
- Clinical presentation consistent with viral meningitis (e.g. headache, neck stiffness, fever, photophobia, phonophobia) and cerebrospinal fluid leukocytes greater than 10 cells/mL
- Clinical presentation consistent with bacterial meningitis (e.g. headache, neck stiffness, fever, altered mental status) and proven bacterial cause by culture, DNA test, or antigen test
- Clinical presentation consistent with encephalitis (e.g. headache, fever, neurological deficits, altered mental status lasting more than 24 hours) as defined by the International Encephalitis Consortium
- Clinical presentation consistent with brain abscess (e.g. headache, neurological deficit, mass lesion on imaging) with proven microbiological cause or response to treatment
- Clinical presentation consistent with neuroborreliosis (e.g. radiculopathy), cerebrospinal fluid pleocytosis greater than 10 leukocytes/mL, and positive intrathecal B.burgdorferi antibody index
- Clinical presentation consistent with neurosyphilis (e.g. encephalitis-like symptoms, dementia, ocular or otogenic syphilis) and positive syphilis serology in serum combined with cerebrospinal fluid leukocytes greater than 10/mL or positive cerebrospinal fluid syphilis antibodies
You will not qualify if you...
- Proven or suspected autoimmune encephalitis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 8 locations
1
Department of Infectious Diseases, Aalborg University Hospital
Aalborg, Denmark, 9000
Actively Recruiting
2
Department of Infectious Diseases, Aarhus University Hospital Skejby
Aarhus, Denmark, 8000
Actively Recruiting
3
Department of Infectious Diseases, Rigshospitalet
Copenhagen, Denmark, 2100
Actively Recruiting
4
Herlev-Gentofte Hospital
Copenhagen, Denmark
Actively Recruiting
5
Department of Pulmonary and Infectious Diseases, Nordsjællands Hospital Hillerød
Hillerød, Denmark, 3400
Actively Recruiting
6
Department of Infectious Diseases, Hvidovre Hospital
Hvidovre, Denmark, 2650
Actively Recruiting
7
Department of Infectious Diseases, Odense University Hospital
Odense, Denmark, 5100
Actively Recruiting
8
Department of Pulmonary and Infectious Diseases, Sjællands University Hospital Roskilde
Roskilde, Denmark, 4000
Actively Recruiting
Research Team
J
Jacob Bodilsen, MD
CONTACT
H
Henrik Nielsen, Professor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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