Actively Recruiting
Prospective Multicenter Screening for Thoracic Disease Via Radiography
Led by Chinese Academy of Sciences · Updated on 2026-05-13
300000
Participants Needed
1
Research Sites
191 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This multicenter, prospective study aims to evaluate the real-world clinical utility of chest X-ray (CXR) for large-scale thoracic disease screening. Adult participants presenting for health examinations will undergo digital CXR screening, and any suspected abnormalities will be confirmed via a gold standard reference, such as a chest CT scan or clinical follow-up. The primary outcome measure is the detection rate (screening yield) of confirmed thoracic conditions. Secondary measures will assess diagnostic accuracy (sensitivity and specificity), false-positive rates, and multi-center reading consistency. By providing prospective, large-cohort evidence, this research seeks to validate the cost-effectiveness and feasibility of CXR in identifying early-stage lung, pleural, and cardiac abnormalities, ultimately guiding public health strategies and optimizing early medical intervention.
CONDITIONS
Official Title
Prospective Multicenter Screening for Thoracic Disease Via Radiography
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18.
- Ability to understand and willingness to sign a written informed consent form.
- Individuals presenting for routine health examinations or community-based screening.
You will not qualify if you...
- Women who are pregnant, lactating, or planning to become pregnant during the study period.
- Physical limitations preventing stable positioning or breath-holding, or presence of metallic implants that may significantly degrade image quality.
- Known history of advanced thoracic diseases currently under treatment (e.g., active lung cancer, end-stage pulmonary fibrosis, or congestive heart failure).
- Individuals who have undergone chest CT or X-ray examinations within the past 3 months.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Dazhou Central Hospital
Dazhou, Sichuan, China
Actively Recruiting
Research Team
Z
Zeyu Zhang, Ph.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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