Low-load resistance muscular training with moderate restriction of blood flow after anterior cruciate ligament reconstruction.
Haruyasu Ohta, Hisashi Kurosawa, Hiroshi Ikeda...
https://pubmed.ncbi.nlm.nih.gov/12635796Actively Recruiting
Phase Not Applicable
Age: 13Years - 17Years
All Genders
ID07015541
Effects of Quadriceps Focused Interventions in Adolescents With ACL Reconstruction
Led by Stanford University · Updated on 2026-04-22
40
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of quadriceps-focused treatments on knee function and movement in adolescents who have undergone anterior cruciate ligament reconstruction (ACLR). The study aims to understand how these interventions impact strength and biomechanics during recovery after ACL surgery in teenagers aged 13 to 17. Participants are randomly assigned to one of two groups. One group receives a 6-week neuromuscular electrical stimulation (NMES) treatment starting the first week after surgery, followed by a 10-week blood flow restriction (BFR) intervention from weeks 7 to 16, along with standard rehabilitation care. The other group receives only the standard physical therapy care, which includes pain and swelling control, restoring knee motion, walking training, strength exercises, and running and jumping activities over 16 weeks. During the study, participants undergo evaluations including isometric knee extension force tests at 16 weeks post-surgery to measure peak force and force steadiness. Additional assessments of hip, knee, and ankle angles during jump landings are also conducted to examine movement patterns. The research includes regular monitoring and rehabilitation visits throughout the 16-week recovery period to track progress and safety.
CONDITIONS
Brief Title
Quadriceps Strengthening ACL Reconstruction
Who Can Participate
Age: 13Years - 17Years
All Genders
Eligibility Criteria
You may qualify if you...
- No history of knee injury or surgery on the opposite leg
You will not qualify if you...
- Bilateral knee injuries
- Prior knee ligament injury and/or surgery
- Multiple ligament injuries and/or ruptures
- Conditions that prevent use of NMES and BFR treatments
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - 16 weeks post-surgery
Participants undergo rehabilitation after ACL reconstruction. This includes a 6-week neuromuscular electrical stimulation (NMES) intervention combined with quadriceps strengthening exercises, followed by a 10-week blood flow restriction (BFR) intervention during compound exercises. Standard physical therapy continues throughout the 16 weeks focusing on pain control, knee range of motion, gait normalization, strength training, running, and plyometrics.
Weekly visits for up to 16 weeks
Trial Site Locations
Total: 1 location
1
Stanford Medicine Children's Health
Sunnyvale, California, United States, 94087
Actively Recruiting
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How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Published Research Related To This Trial
Effects of neuromuscular electrical stimulation after anterior cruciate ligament reconstruction on quadriceps strength, function, and patient-oriented outcomes: a systematic review.
Kyung-Min Kim, Ted Croy, Jay Hertel...
https://pubmed.ncbi.nlm.nih.gov/20592480