Actively Recruiting

Age: 18Years +
FEMALE
ID03794466

Quantification of Pain Relief With Gonadal Vein Embolization for Pelvic Congestion Syndrome

Led by University of Kansas Medical Center · Updated on 2026-03-23

30

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Chronic pelvic pain affects nearly 40% of women during their lifetime, with pelvic congestion syndrome (PCS) responsible for up to 30% of these cases. PCS is caused by problems in the gonadal veins, leading to painful swelling in the pelvic veins. While medical treatments aim to reduce ovarian function and tighten the veins, they often provide limited and short-term relief. This research aims to measure how much pain relief patients experience after undergoing coil embolization of the gonadal veins and to identify factors that predict better or worse outcomes. Participants will have coil embolization of the gonadal veins, a procedure performed to block the veins causing the congestion. This study observes patients treated in the Interventional Radiology division between October 2018 and October 2019. The degree of pain relief will be assessed over time, focusing especially on changes from before the procedure to one year after. Women in the study will be assessed using the Pelvic Congestion Symptom Pain Scale at baseline and up to 360 days after the embolization. Researchers will monitor pain levels and analyze clinical or imaging characteristics that might predict treatment response. The total participation time covers one year post-procedure, during which pain and treatment outcomes will be carefully tracked.

CONDITIONS

Brief Title

Quantify the Degree of Pain Relief of Pelvic Congestion Syndrome Following Gonadal Vein Embolization

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female patients 18 years of age or older
  • Meet the clinical and imaging criteria for the diagnosis of PCS and have no contraindications to coil embolization of the gonadal veins
  • Patients treated with coil embolization of the gonadal veins in the Interventional Radiology division between October 1, 2018 to October 1, 2019
Not Eligible

You will not qualify if you...

  • Patients less than 18 years of age
  • Patients with an underlying cause of pelvic congestion syndrome unrelated to venous congestion and insufficiency, including nutcracker syndrome or a mass causing compression of the gonadal veins
  • Patients who have received prior surgical therapy for PCS, including bilateral salpingo-oophorectomy, gonadal vein resection, or gonadal vein ligation

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Observational Monitoring

Duration - Up to 12 months after the procedure

Participants who have undergone gonadal vein embolization are observed to quantify pain relief over time using the Pelvic Congestion Symptom Pain Scale.

Trial Site Locations

Total: 1 location

1

The University of Kansas Medical Center

Kansas City, Kansas, United States, 66160

Actively Recruiting

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Research Team

C

Carissa Walter, MPH

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Published Research Related To This Trial

Effectiveness of Embolization or Sclerotherapy of Pelvic Veins for Reducing Chronic Pelvic Pain: A Systematic Review.

Jane P Daniels, Rita Champaneria, Laila Shah...

https://pubmed.ncbi.nlm.nih.gov/27397619

A Randomized Trial of Endovascular Embolization Treatment in Pelvic Congestion Syndrome: Fibered Platinum Coils versus Vascular Plugs with 1-Year Clinical Outcomes.

Jose A Guirola, Maria Sánchez-Ballestin, Sergio Sierre...

https://pubmed.ncbi.nlm.nih.gov/29174618