Actively Recruiting

Phase Not Applicable
Age: 5Years - 60Years
All Genders
NCT06819449

Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy Patients

Led by South Valley University · Updated on 2025-02-11

50

Participants Needed

1

Research Sites

52 weeks

Total Duration

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AI-Summary

What this Trial Is About

Mycobacterium leprae is a slow-growing bacillus that causes leprosy. the infection may take two to ten years to incubate. While the exact mechanism of infection transmission is unknown, direct bacillus absorption through the nasal or respiratory mucosa and aerosolized nasal secretions are the most common theories. The bacteria is subsequently transported by the bloodstream to the peripheral nerves, where it can result in tissue damage from painless burns and ulcers as well as irreparable nerve damage that results in a loss of protective feeling.

CONDITIONS

Official Title

Rab 32 Gene Polymorphisms as a Prognostic Factor in Leprosy Patients

Who Can Participate

Age: 5Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients of both sexes with positive slit skin smear for m.leprae.
Not Eligible

You will not qualify if you...

  • Patients with hypersensitivity to sulfa drugs.
  • Patients with hypersensitivity to clofazimine or rifampicin.
  • Pregnant or lactating women.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Qina University hospital, South Valley University Hospital

Qina, Egypt

Actively Recruiting

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Research Team

L

Lydia Atef Nassief, MSc

CONTACT

E

Eisa Mohammed Hegazy, Assist. Prof

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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