Actively Recruiting
Randomized Controlled Trial of the Effects of Combined Resistance and AerobiC Exercise on Health-related Quality of Life in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer (REACH)
Led by Rigshospitalet, Denmark · Updated on 2026-05-13
150
Participants Needed
4
Research Sites
258 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary objective of this trial is to compare the effects of 18 weeks structured exercise training versus on control on healt-related quality of life in patients with mCRC undergoing first-line chemotherapy.
CONDITIONS
Official Title
Randomized Controlled Trial of the Effects of Combined Resistance and AerobiC Exercise on Health-related Quality of Life in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer (REACH)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults (≥18 years of age) scheduled to undergo first-line chemotherapy for metastatic colorectal cancer.
You will not qualify if you...
- Pregnancy.
- Life expectancy less than 6 months.
- Absolute contraindications to maximal exercise according to Danish Society of Cardiology guidelines.
- Eastern Cooperative Oncology Group (ECOG) performance status greater than 2.
- Inability to understand Danish or English.
- Participation in structured moderate-to-high intensity aerobic exercise for more than 30 minutes at least once per week in the past 3 months.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 4 locations
1
Centre for Physical Activity Research, Copenhagen Univerisity Hospital - Rigshospitalet
Copenhagen, Denmark, 2100
Actively Recruiting
2
Herlev and Gentofte Hospital
Herlev, Denmark, 2730
Actively Recruiting
3
North Zealand University Hospital, Hillerød
Hillerød, Denmark, 3400
Actively Recruiting
4
Zealand University Hospital, Roskilde
Roskilde, Denmark, 4000
Actively Recruiting
Research Team
C
Casper Simonsen, Phd
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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