Study on Respiratory Syncytial Virus Infection During COPD Exacerbations Investigating RSV Impact on Outcomes in Adults 50 and Older

What this Trial Is About

Researchers are examining the presence of respiratory syncytial virus RSV infection in adults aged 50 and older who have chronic obstructive pulmonary disease COPD and experience worsening symptoms during the RSV season from October to April. This observational study aims to find out how common RSV infection is among these patients and whether it leads to more severe outcomes like hospitalization, longer hospital stays, heart problems, or death. The study compares patients who test positive for RSV with those who do not to understand the impact of the virus on COPD exacerbations. Participants will receive standard medical care for COPD exacerbations, including long-acting bronchodilators and inhaled corticosteroids, and may take antibiotics or oral corticosteroids if needed during their hospital stay. Diagnostic testing for RSV infection is done as part of routine care during their visit to the emergency department or day hospital. The study observes two groups based on whether their exacerbations occur during or outside the RSV season. Throughout the study, participants will provide demographic and clinical information like medical history, COPD severity, other health conditions, and past exacerbation events. Researchers will monitor key outcomes such as hospitalization rates, length of hospital stay, acute cardiovascular events, and mortality during the exacerbation period. The main measurement is the prevalence of RSV infection during COPD exacerbations in the RSV season, tracked over one year.

Respiratory Syncytial Virus Infection in Exacerbations of Chronic Obstructive Pulmonary Diasease: the RECODE Study