Analysis of Risk Factors for Complications After Major Abdominal, Orthopedic, or Vascular Surgery in Adults

What this Trial Is About

Researchers are analyzing factors that contribute to complications after major non-heart surgery in adults. This analysis focuses on a large group of patients who had major abdominal, orthopedic, or vascular surgery lasting more than two hours under general anesthesia. The study examines how patient condition, surgical factors, and management during surgery relate to postoperative morbidity and mortality. It is a post-hoc analysis of data collected in the OPHIQUE study, which originally evaluated intraoperative management guided by tissue oxygenation markers. This research does not involve study drugs or treatments but observes patients who underwent surgery. It compares groups of patients who experienced postoperative complications with those who did not, looking at risk factors such as age, comorbidities, and surgical conditions. The goal is to identify factors associated with complications within two years after surgery, including risks for kidney problems. Participants are adults who had major surgery and meet specific health criteria. The study collects data on their surgical outcomes and health status over two years. Researchers assess the number of risk factors linked to postoperative morbidity, mortality, and renal dysfunction. No additional treatments are administered, and participation involves observation and data collection. The study runs from June 2022 to June 2026.

Risk Factors for Postoperative Complications in Major Non-cardiac Surgery: Post-hoc Analysis of the OPHIQUE Multicentre Study