Actively Recruiting

Phase Not Applicable
Age: 18Years - 85Years
All Genders
ID07095036

Generating Artificial Sensory Perceptions Using Spinal Cord Stimulation

Led by University of North Carolina, Chapel Hill · Updated on 2026-02-04

10

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

U

University of North Carolina, Chapel Hill

Lead Sponsor

N

National Institute of Neurological Disorders and Stroke (NINDS)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are studying how spinal cord stimulation (SCS) can create different sensations and how these sensations change when stimulation settings are adjusted. The study focuses on people undergoing SCS implantation to manage chronic pain. This research aims to better understand sensory perceptions produced by spinal stimulation to improve future treatments. Participants will have SCS trial leads implanted as part of their usual care for chronic pain. Before these leads are removed, they will visit the clinic where the clinical stimulator will be disconnected and replaced with a research stimulator. While seated, participants will use a touchscreen to perform tasks involving choosing between two options as spinal stimulation is delivered. Audio and video recordings will be made during these sessions, and epidural signals will be collected through the leads. During the study, researchers will measure the minimum stimulation needed to evoke sensory perceptions and the change in stimulation required to notice differences in these sensations. This monitoring occurs from the time the leads are implanted until one week after they are removed. Participants will be closely observed throughout the process, with the study lasting from implantation to lead explantation and assessment within that one-week period.

CONDITIONS

Brief Title

Sensory Spinal Cord Stimulation

Who Can Participate

Age: 18Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male and female patients 18-85 years old
  • Undergoing spinal cord stimulation implantation for treatment of chronic pain
  • Ability to walk 10 meters without assistance
  • Provides written consent for the study
Not Eligible

You will not qualify if you...

  • High risk of falling
  • Refusal to participate in the study
  • Lack of capacity to give consent

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Treatment

Duration - Approximately 1 week from lead implantation to lead explantation

Participants undergo spinal cord stimulation through implanted trial leads and perform psychophysical tasks with external research stimulators while seated.

Multiple clinic visits during the week for stimulation and task participation

Trial Site Locations

Total: 1 location

1

Ambulatory Care Center

Chapel Hill, North Carolina, United States, 27514

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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