Actively Recruiting
Sex-differential Host-microbiome CVD Risk - A Longitudinal Cohort Approach
Led by Charite University, Berlin, Germany · Updated on 2024-02-09
200
Participants Needed
1
Research Sites
278 weeks
Total Duration
On this page
Sponsors
C
Charite University, Berlin, Germany
Lead Sponsor
D
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The XCVD study investigates the influence of sex hormones on the composition of the gut microbiome and the possible emergence of cardiovascular risk factors. It will follow 200 healthy transgender individuals for two years during their hormone replacement therapy (HRT) and analyze them for the possible emergence of cardiovascular risk factors in relation to changes in the gut microbiome, metabolome, and immunome. We would also like to phenotype cardiovascular disease.
CONDITIONS
Official Title
Sex-differential Host-microbiome CVD Risk - A Longitudinal Cohort Approach
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-50
- Ability to understand and speak German or English
- Previous gender hormone replacement therapy (HRT)
- Ability to give informed written consent
- Health insurance coverage for follow-up of incidental findings
You will not qualify if you...
- Any diseases or functional disorders that prevent participation as judged by the study physician
- Inability to understand the nature, significance, and scope of the study or to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Experimental and Clinical Research Center, Clinical Research Unit
Berlin, Germany, 13125
Actively Recruiting
Research Team
S
Sofia Forslund, Prof. Dr.
CONTACT
L
Lajos Marko, Dr.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here