Screening for Cervical and Endometrial Cancer in Transgender and Gender Diverse Adults Seeking Hysterectomy

What this Trial Is About

This research aims to evaluate the rates of cervical cancer screening and endometrial sampling before gender-affirming hysterectomy in transgender and gender diverse TGD individuals. The study seeks to assess the need for these tests in this population and explore patient-centered options to improve care. By linking screening status with hysterectomy pathology, it provides preliminary data on current guideline adherence and informs future evidence-based guidelines. The study is observational and does not involve an intervention. It compares standard cancer screening methods with options like HPV self-testing to see how these choices may influence screening rates and patient experiences. Participants include those who have had or plan to have a hysterectomy, focusing on capturing real-world screening practices. Participants will be observed over a 36-month period, during which researchers will measure screening and sampling rates and effects of HPV self-testing options. The study collects patient experience data and evaluates whether offering self-testing changes screening behavior. All assessments are observational without treatment administration, with follow-up continuing through the study duration.

Cervical and Endometrial Cancer Screening in Patients Seeking Gender-Affirming Hysterectomy