Actively Recruiting

Age: 15Years - 49Years
All Genders
Healthy Volunteers
ID03830879

Shenzhen Birth Cohort Study to Investigate Early Life Environmental Impacts on Maternal and Child Health in Shenzhen, China

Led by Sun Yat-sen University · Updated on 2019-02-05

10000

Participants Needed

1

Research Sites

408 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating how early life environmental exposures affect both short- and long-term health outcomes in Shenzhen, China. This observational study, called the Shenzhen Birth Cohort Study, is supported by Shenzhen city and Nanshan district and aims to provide evidence for the Developmental Origins of Health and Disease (DOHaD) hypothesis. The study focuses on understanding childhood diseases and involves experts from public health fields, including professors and associate professors. The study plans to recruit 10,000 pregnant women in early pregnancy and follow them and their children for seven years. Biological samples and questionnaires will be collected to monitor child growth, development, and health. There is no treatment or intervention being tested in this cohort study. Participants will have multiple assessments during pregnancy, delivery, and postnatal periods. These include tracking fetal outcomes at delivery, maternal weight changes at key pregnancy stages, the presence of gestational complications, and postnatal depression up to six months after delivery. Children's physical and neurodevelopment will be evaluated periodically from 1 month to 6 years old. The study spans from early pregnancy through a seven-year follow-up period to gather comprehensive health data.

CONDITIONS

Brief Title

Shenzhen Birth Cohort Study

Who Can Participate

Age: 15Years - 49Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant women planning to deliver and participate in child care at the study hospital
  • Pregnant women planning to reside in Shenzhen for at least 7 years
  • Pregnant women interested in the study and willing to provide informed consent
  • Gestational age less than 20 weeks
  • Agreement for the newborn to be included and followed regularly in the child health clinic until age 7
Not Eligible

You will not qualify if you...

  • Pregnant women with gestational age greater than 20 weeks
  • Those who refuse to participate
  • Unable to guarantee delivery or child care participation at the study hospital
  • Mentally incapacitated individuals requiring guardians
  • Unwilling to sign informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surveillance

Duration - Up to delivery (about 7 months)

Participants are observed during pregnancy and delivery to collect data on maternal and fetal health outcomes.

Visits at pre-pregnancy period, 20 weeks, 28 weeks of gestation, before labor, and at delivery

Long-term Monitoring

Duration - Up to 7 years after delivery

Participants and their children are followed to assess child growth, development, and health up to 7 years.

Visits at 30 days, 3 months, 6 months, 1 year, 3 years, 5 years, and 6 years after delivery

Trial Site Locations

Total: 1 location

1

RuiGao

Shenzhen, Guangdong, China, 510000

Actively Recruiting

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Research Team

L

Li Cai

L

Lihua Huang

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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