Interrupted time series analysis in drug utilization research is increasing: systematic review and recommendations.
Racquel Jandoc, Andrea M Burden, Muhammad Mamdani...
https://pubmed.ncbi.nlm.nih.gov/25890805Actively Recruiting
Phase Not Applicable
Age: 16Years - 30Years
All Genders
ID07561957
A Smart Phone Application to Improve Adoption of the 2024 Kidney Disease Improving Global Outcomes (KDIGO) Chronic Kidney Disease (CKD) Guidelines
Led by St. James's Hospital, Ireland · Updated on 2026-05-01
80
Participants Needed
2
Research Sites
21 weeks
Total Duration
On this page
Sponsors
S
St. James's Hospital, Ireland
Lead Sponsor
U
University of Dublin, Trinity College
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating whether using a digital smartphone application can help adults with chronic kidney disease (CKD) better follow the 2024 Kidney Disease: Improving Global Outcomes (KDIGO) guidelines. The study focuses especially on young adults transitioning from pediatric to adult nephrology care, who face higher risks and challenges during this vulnerable period. The research aims to improve treatment adherence and health outcomes by addressing gaps in current care and guideline implementation. Participants will use a modified version of the St. James's Hospital Renal App, which has been adapted to align with the KDIGO 2024 guidelines. The app provides tailored recommendations, reminders, educational materials, and collects patient-reported outcomes. The study uses a randomized stepped wedge design where patients receive first exposure and later continued use of the app. The intervention supports healthcare providers by highlighting opportunities for evidence-based therapies and helps patients manage their care digitally. During the study, participants will be monitored for changes in adherence to KDIGO guidelines over 18 months. Assessments will include patient engagement, clinical data integration via electronic health records, and patient-reported measures. The app also supports appointment management and medication reminders, aiming to enhance self-management and slow CKD progression. The research includes diverse patient subgroups and considers cultural and linguistic needs to promote equitable care.
CONDITIONS
Brief Title
A Smart Phone Application to Improve Adoption of the 2024 Kidney Disease Improving Global Outcomes (KDIGO) Chronic Kidney Disease (CKD) Guidelines
Who Can Participate
Age: 16Years - 30Years
All Genders
Eligibility Criteria
You may qualify if you...
- Adults aged 60 16 years
- Diagnosed with chronic kidney disease stages 1 to 5
- Owns a smartphone and is capable of using mobile applications
- Provides informed consent
You will not qualify if you...
- Unable to provide informed consent due to neurocognitive impairment
- Age 30 years or older
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Implementation
Duration - Up to 18 months
Participants use a KDIGO-aligned smartphone application designed to improve adherence to chronic kidney disease management guidelines.
Ongoing app engagement with periodic clinical assessments as per routine care
Trial Site Locations
Total: 2 locations
1
St. James's Hospital
Dublin, Ireland
Actively Recruiting
2
Trinity College Dublin
Dublin, Ireland
Actively Recruiting
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Research Team
D
Dr Susan M McAnallen, MB BCh BAO
P
Prof Donal J Sexton, MB BCh BAO BSc, MRCPI, MD, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
2
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K Hemming, T P Haines, P J Chilton...
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https://pubmed.ncbi.nlm.nih.gov/28822830Establishing core outcome domains in pediatric kidney disease: report of the Standardized Outcomes in Nephrology-Children and Adolescents (SONG-KIDS) consensus workshops.
Camilla S Hanson, Jonathan C Craig, Charlotte Logeman...
https://pubmed.ncbi.nlm.nih.gov/32628942