Actively Recruiting

Phase Not Applicable
Age: 25Years - 45Years
All Genders
NCT07428187

Snacking Effects on the Brain Response to Foods and Satiety During Dieting

Led by University of Colorado, Denver · Updated on 2026-03-23

70

Participants Needed

1

Research Sites

108 weeks

Total Duration

On this page

Sponsors

U

University of Colorado, Denver

Lead Sponsor

C

California Walnut Commission

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study plans to learn more about how different types of snacks may affect brain processes relating to eating behaviors during a diet intervention.

CONDITIONS

Official Title

Snacking Effects on the Brain Response to Foods and Satiety During Dieting

Who Can Participate

Age: 25Years - 45Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 25 and 45 years
  • Body Mass Index (BMI) of at least 27 kg/m2
  • Comfortable completing a weight-loss diet program
  • Willing to eat a daily snack of walnuts or pretzels provided by the study
Not Eligible

You will not qualify if you...

  • Allergy to nuts or wheat
  • History of bariatric surgery
  • Current eating disorder
  • Current use of illicit substances
  • Currently pregnant, breastfeeding, or less than 6 months postpartum
  • Uncontrolled high blood pressure (greater than 160/100 mmHg)
  • Significant endocrine, metabolic, kidney, liver, or blood diseases affecting study results
  • Use of injectable diabetes medications, sulfonylureas, or meglitinides
  • Use of weight-loss medications or steroids within about 3 months before the study
  • Recent significant mental health changes or hospitalizations related to mental health
  • Neurological illness or injury affecting MRI data
  • Weight change greater than 10% within 3 months before the study
  • Participation in another weight-loss study
  • Not comfortable eating study-provided meals or following a highly restrictive diet
  • MRI-specific exclusions such as metal in the body or weight over 500 pounds

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Colorado Anschutz Medical Campus

Aurora, Colorado, United States, 80045

Actively Recruiting

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Research Team

A

Allison Hild, BS

CONTACT

K

Kristina T Legget, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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Snacking Effects on the Brain Response to Foods and Satiety During Dieting | DecenTrialz