Actively Recruiting

Phase Not Applicable
Age: 18Years - 25Years
All Genders
ID06898554

Cross-Education Effect of Structured Balance Training Program on Spinal and Supraspinal Control in Athletes With Chronic Ankle Instability

Led by Ayca Yagcioglu · Updated on 2025-03-27

30

Participants Needed

2

Research Sites

4 weeks

Total Duration

On this page

Sponsors

A

Ayca Yagcioglu

Lead Sponsor

Y

Yeditepe University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are investigating chronic ankle instability (CAI) in athletes, a condition often resulting from repeated ankle sprains that affect neuromuscular control such as proprioception and strength. Damage to ankle ligaments and nerves may alter the nervous system, causing balance and joint stability problems. The study aims to explore how unilateral balance training might improve control at spinal and brain levels through a process called cross-education. The study involves a 6-week structured balance training program consisting of seven exercises focused on balance and hop stabilization. Participants with unilateral CAI will be randomly assigned to one of three groups: training on the stable ankle, training on the unstable ankle, or no intervention. This approach helps researchers understand the effects of the training on both the injured and uninjured sides. Participants will be evaluated at the start and end of the 8-week intervention period using assessments of proprioception, brain stimulation, and reflexes. Additional measures include questionnaires on ankle instability and foot and ankle function. The study monitors changes in static and dynamic balance and neural excitability to determine how the training impacts ankle stability and control.

CONDITIONS

Brief Title

Spinal and Supraspinal Control in Chronic Ankle Instability

Who Can Participate

Age: 18Years - 25Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Volunteering to participate in the study
  • Being an athlete between the ages of 18-25
  • Playing a field team sport such as basketball, volleyball, or handball
  • Having a history of at least 2 significant grade II lateral ankle sprains diagnosed by a physician
  • Experiencing related inflammatory symptoms or "giving away" sensation with a score of 25 or less on the Cumberland Ankle Instability Tool
  • Scoring less than 90% on the activities of daily living subscale and less than 80% on the sport subscale of the Foot and Ankle Ability Measure
  • Having recurrent episodes of lateral ankle sprains on the injured ankle within the past 12 months
Not Eligible

You will not qualify if you...

  • Having an acute injury of lower extremity musculoskeletal structures in the last three months
  • Having had orthopedic surgery in any of the lower extremities
  • Having bilateral ankle instability
  • Having a vestibular or balance disorder

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 8 weeks

Participants undergo a structured balance training protocol consisting of 7 exercises including balance and hop stabilization exercises targeted to either the stable or unstable ankle depending on group assignment. The control group does not receive any intervention.

Visits at baseline and end of the 8-week intervention

Trial Site Locations

Total: 2 locations

1

Yeditepe University Koşuyolu Hospital

Istanbul, Turkey (Türkiye), 34718

Actively Recruiting

2

Yeditepe University

Istanbul, Turkey (Türkiye), 34755

Actively Recruiting

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Research Team

A

Ayca Yagcioglu, MSc

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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