Actively Recruiting
Effect of ACL Reconstruction Using Peroneus Longus Versus Hamstring Autografts on Biomechanical Properties of Ankle Joint Complex
Led by Cairo University · Updated on 2024-10-08
40
Participants Needed
1
Research Sites
34 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Anterior cruciate ligament (ACL) injuries are common, especially among young adults and women, and contribute significantly to knee instability. This research investigates the effects of ACL reconstruction using two different tendon grafts—the Peroneus longus tendon (PLT) autograft and the Hamstring tendon (HT) autograft—on the biomechanical properties of the ankle joint complex. The study aims to understand how these grafts influence ankle stability and postural control after surgery, given concerns that PLT grafts might affect ankle proprioception and balance due to their donor site in the ankle. Participants undergo ACL reconstruction with either a PLT or HT autograft. The study measures outcomes using isokinetic dynamometer tests to assess peak torques of ankle plantarflexors and evertors. Functional balance is evaluated through the modified Star Excursion Balance Test and the Single Leg Stance test. These assessments are conducted preoperatively, and then repeated at three and six months post-surgery to compare the effects of the two graft types on ankle strength and balance. Throughout the study, participants are closely monitored for changes in ankle strength and stability. Researchers collect data on peak torque, balance test performance, and single-leg stance duration at three time points. The study uses a randomized design with single masking to ensure objective evaluation. Participants are between 15 and 45 years old with isolated ACL tears and healthy ankles before surgery. The total duration of follow-up is six months after surgery, allowing comparison of recovery and biomechanical outcomes between the two graft methods.
CONDITIONS
Brief Title
Effect of ACL Reconstruction in Biomechanical Properties of Ankle Joint Complex
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age ranging between 15- 45 years
- Having unilateral isolated ACL tear with no concomitant tear of other ligaments of the knee
- Having no evidence of meniscal repair
- Having bilateral healthy ankle before surgery.
You will not qualify if you...
- Pre-existing ankle injury or ankle instability
- Associated ligament injury, chondral damage, meniscal injury, fracture around the knee, and presence of pathologic condition in the lower extremity or an abnormal contralateral knee joint.
- Visible mal-alignments in the lower extremities.
- Previous surgery to the affected knee.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Preoperative through 6 months post-surgery
Participants undergo ACL reconstruction with either Peroneus longus tendon autograft or Hamstring tendon autograft and have biomechanical testing of ankle joint function.
3 visits (preoperative, 3 months, and 6 months post-surgery)
Trial Site Locations
Total: 1 location
1
Cairo University
Cairo, Egypt, 11865
Actively Recruiting
Research Team
L
Lena ElBadawy, Bachelor's degree
L
Lamyaa Kotb Elsayad, PHD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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