Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07139938

Spontaneous Correction of Sagittal Imbalance After Isolated Lumbar Decompression

Led by N.N. Priorov National Medical Research Center of Traumatology and Orthopedics · Updated on 2025-12-11

165

Participants Needed

3

Research Sites

104 weeks

Total Duration

On this page

Sponsors

N

N.N. Priorov National Medical Research Center of Traumatology and Orthopedics

Lead Sponsor

B

Burdenko Neurosurgery Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

Sagittal spinal imbalance may be caused by orthopedic problems, compression of the neural structures of the spinal canal, and pain syndrome (functional imbalance). Sagittal imbalance in combination with appropriate clinical symptoms may require surgical correction of the spine with fixation. However, in some cases, patients experience spontaneous correction of sagittal balance after isolated decompression without any correction or fusion. Therefore, it is necessary to clarify whether isolated decompression may cause spontaneous correction of sagittal imbalance in patients with degenerative lumbar stenosis.

CONDITIONS

Official Title

Spontaneous Correction of Sagittal Imbalance After Isolated Lumbar Decompression

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 45 and over
  • Radicular leg pain and/or neurogenic claudication with or without back pain caused by single- or multi-level degenerative lumbar stenosis confirmed by MRI
  • Planned isolated decompression of the spinal canal without implantation of any devices
  • Symptoms persisting for at least 3 months prior to surgery
  • Given written informed consent
  • Able and agree to fully comply with the clinical protocol and follow-up schedule
Not Eligible

You will not qualify if you...

  • Prior any lumbar surgery
  • Scoliosis of any non-degenerative cause
  • Degenerative scoliosis greater than 20 degrees
  • Contraindication or inability to undergo baseline or follow-up MRI or X-ray
  • Any condition that may interfere with safety or study conduct as judged by investigator
  • Performed intraoperative discotomy
  • Performed intraoperative iatrogenic instability of the lumbar segment (e.g., facetectomy, foraminotomy)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Pirogov National Medical Surgical Center

Moscow, Russia, 105203

Actively Recruiting

2

Burdenko Neurosurgery Institute

Moscow, Russia, 125047

Actively Recruiting

3

Priorov National Medical Research Center of Traumatology and Orthopedics

Moscow, Russia, 127299

Actively Recruiting

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Research Team

A

Aleksandr Krutko, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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