Prospective Multicenter Study of Surgery for Complex Adult Spinal Deformity Evaluating Outcomes, Complications, and Best Practices

What this Trial Is About

Researchers are evaluating surgical outcomes and best practice guidelines for adults with complex spinal deformities. This study focuses on patients with adult spinal deformity ASD, examining radiographic and clinical results, surgical and postoperative complications, risk factors for revision surgeries, and the impact of standard care processes on improving patient outcomes and reducing complications. The research aims to develop a universal system for classifying spine surgery complications and to understand factors affecting costs and mental health in ASD patients. The study involves multicenter, prospective observation of adults undergoing surgery for complex ASD, including those with congenital, degenerative, idiopathic, or iatrogenic spinal deformities. Complex cases are defined by specific radiographic measurements, extensive spinal fusion procedures, or geriatric criteria. Surgical interventions are determined by each patients treating surgeon and may include procedures like three-column osteotomies or anterior column reconstruction. Researchers also assess blood management, opioid use, frailty, and mental health as parts of the treatment process. Participants will undergo full-body EOS radiographic assessments before surgery, with follow-up evaluations at 3 months, 1, 2, 5, and 10 years. Outcomes are measured using various tools including the Scoliosis Research Society 22r questionnaire, Oswestry Disability Index, Veterans RAND 12, and PROMIS scales for anxiety, depression, pain, physical function, and social satisfaction. The study also tracks adverse events, frailty scores, and hospital stay lengths to understand long-term clinical and social health outcomes. The study will continue monitoring participants through 2032 to gather comprehensive data on surgical effectiveness and patient well-being.

Complex Adult Deformity Surgery (CADS)