Actively Recruiting
Complex Adult Deformity Surgery (CADS)
Led by International Spine Study Group Foundation · Updated on 2026-02-17
1500
Participants Needed
18
Research Sites
730 weeks
Total Duration
On this page
Sponsors
I
International Spine Study Group Foundation
Lead Sponsor
M
Medtronic
Collaborating Sponsor
AI-Summary
What this Trial Is About
Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.
CONDITIONS
Official Title
Complex Adult Deformity Surgery (CADS)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of adult congenital, degenerative, idiopathic or iatrogenic spinal deformity
- Full body EOS radiographic assessment (sagittal and coronal visualization from skull to foot)
- Meet at least one complex patient criteria:
- Radiographic: PI-LL 6 25 degrees, TPA 6 30 degrees, SVA > 15 cm, thoracic scoliosis 6 70 degrees, thoracolumbar/lumbar scoliosis 6 50 degrees, or global coronal malalignment > 7 cm
- Procedural: posterior spinal fusion of more than 12 levels, or 3 column osteotomy or anterior column reconstruction
- Geriatric: age over 65 years and at least 7 levels of spinal instrumentation during surgery
You will not qualify if you...
- Age under 18 years
- Active spine tumor or infection
- Deformity caused by acute trauma
- Neuromuscular diseases such as Parkinson's, Multiple Sclerosis, or Post-polio syndrome
- Syndromic scoliosis
- Inflammatory arthritis or autoimmune diseases like Rheumatoid arthritis, Lupus, or Ankylosing Spondylitis
- Prisoners
- Women who are pregnant
- Patients who do not speak English
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 18 locations
1
Shiley Center for Orthopaedic Research and Education at Scripps Clinic
La Jolla, California, United States, 92037
Actively Recruiting
2
University of California, Davis, Department of Orthopedic Surgery
Sacramento, California, United States, 05616
Active, Not Recruiting
3
UCSF, Department of Neurosurgery
San Francisco, California, United States, 94143
Actively Recruiting
4
Denver International Spine Center, Rocky Mountain Hospital for Children and Presbyterian St. Luke's Medical Center
Denver, Colorado, United States, 80218
Actively Recruiting
5
University of Kansas, Department of Orthopedic Surgery
Kansas City, Kansas, United States, 66160
Actively Recruiting
6
Norton Leatherman Spine Center
Louisville, Kentucky, United States, 40207
Actively Recruiting
7
Spine Institute of Louisiana
Shreveport, Louisiana, United States, 71101
Actively Recruiting
8
John Hopkins University, Department of Orthopedic Surgery
Baltimore, Maryland, United States, 21224
Actively Recruiting
9
NYU, Department of Orthopedics
New York, New York, United States, 10016
Actively Recruiting
10
Hospital for Special Surgery, Department of Orthopedic Surgery
New York, New York, United States, 10021
Actively Recruiting
11
Columbia University Medical Center
New York, New York, United States, 10032
Actively Recruiting
12
Northwell Health
New York, New York, United States, 10075
Actively Recruiting
13
Duke University Health System
Durham, North Carolina, United States, 27710
Actively Recruiting
14
University Orthopedics
Providence, Rhode Island, United States, 02905
Actively Recruiting
15
Medical City Spine Hospital - Southwest Scoliosis Institute
Dallas, Texas, United States, 75243
Actively Recruiting
16
University of Texas - Houston
Houston, Texas, United States, 77030
Actively Recruiting
17
University of Virginia
Charlottesville, Virginia, United States, 22908
Actively Recruiting
18
Toronto Western
Toronto, Ontario, Canada
Actively Recruiting
Research Team
C
Christine Baldus, MS
CONTACT
R
Ray Pinteric
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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