Actively Recruiting
SSM Predicts Outcomes of CLD Inpatients With Acute Liver Injury
Led by Nanfang Hospital, Southern Medical University · Updated on 2025-05-21
411
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In this study, a single non-invasive tool, spleen stiffness measurement (SSM), was used to monitor the disease regression of inpatients with chronic liver disease (CLD) and acute liver injury. The present study aimed to establish an early diagnosis warning model for acute-on-chronic liver failure (ACLF) by SSM and investigate the effect of dynamic changes in SSM on the short-term prognosis (28-day, 90-day morbidity and mortality) of inpatients with CLD and acute liver injury.
CONDITIONS
Official Title
SSM Predicts Outcomes of CLD Inpatients With Acute Liver Injury
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 years and 80 years
- Chronic liver diseases regardless of cause
- Acute liver injury with total bilirubin 3 mg/dl or higher regardless of cause
You will not qualify if you...
- Prior liver-related surgeries such as liver transplantation, TIPS, splenectomy, or partial splenic embolization
- Severe extrahepatic diseases like advanced chronic obstructive pulmonary disease, end-stage kidney failure, or recent heart attack within 3 months
- Use of immunosuppressive drugs for reasons other than chronic liver disease
- Diagnosis of liver cancer or other cancers during screening
- Serious mental illnesses including anxiety, depression, OCD, or PTSD
- Pregnancy
- Jaundice caused by biliary obstruction or cholestasis
- Any condition that investigators judge unsuitable for participation
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Hepatology Unit, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University
Guangzhou, Guangdong, China, 510515
Actively Recruiting
Research Team
J
Jinjun Chen, PHD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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