Actively Recruiting
A Study to Evaluate Splenectomy on Debridement for Acute Necrotizing Pancreatitis With Pancreatic Sinistral Portal Hypertension
Led by Zhejiang University · Updated on 2025-07-23
66
Participants Needed
1
Research Sites
134 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is a prospective, single-center, randomized controlled trial focusing on patients with acute necrotizing pancreatitis (ANP) complicated by pancreatic sinistral portal hypertension (PSPH). The study aims to study the impact of total splenectomy on the debridement efficacy, perioperative recovery, and prognosis of patients with ANP complicated by PSPH.
CONDITIONS
Official Title
A Study to Evaluate Splenectomy on Debridement for Acute Necrotizing Pancreatitis With Pancreatic Sinistral Portal Hypertension
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years
- Acute necrotic pancreatitis complicated by pancreatic sinistral portal hypertension
- Patients undergoing open debridement for infected pancreatic necrosis
You will not qualify if you...
- Pre-existing heart, lung, liver, kidney, or other organ failure prior to acute pancreatitis
- Pre-existing conditions such as cirrhosis that may cause portal hypertension prior to acute pancreatitis
- Pre-existing hematological diseases prior to acute pancreatitis
- Patients undergoing laparoscopic or nephroscopic debridement
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310003
Actively Recruiting
Research Team
Y
Yun Zhang
CONTACT
J
Jian Zhang
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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