Actively Recruiting
A Study of Adaptive Radiotherapy of Head-neck Cancer Using Daily Replanning and Optimization of the Treatment Plan.
Led by Rigshospitalet, Denmark · Updated on 2026-04-02
40
Participants Needed
1
Research Sites
262 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Radiotherapy of head-neck cancer is associated with significant side effects. Using daily online adaptive radiotherapy to account for the changing anatomy, radiation to organs at risk can be lowered. We will investigate whether this is feasible and associated with a reduction in the risk of toxicity.
CONDITIONS
Official Title
A Study of Adaptive Radiotherapy of Head-neck Cancer Using Daily Replanning and Optimization of the Treatment Plan.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically confirmed squamous cell carcinoma of the pharynx or larynx
- Planned for primary radiotherapy with curative intent
- No current or previous malignancies that could affect treatment or evaluation
- Provided informed consent as required by law
- Not participating in conflicting protocols
- Cancer stage I-IV excluding T1-T2N0 carcinoma of the glottic larynx
- ECOG/WHO performance status 0-2
You will not qualify if you...
- Cancers of the glottic larynx at stage I/II, skull base, sino-nasal area, or unknown primary tumor
- Unable to attend full course of radiotherapy or follow-up visits
- Presence of distant metastasis
- Previous radiotherapy of the head and neck
- Previous surgery for the primary cancer with curative intent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Rigshospitalet
Copenhagen, Denmark
Actively Recruiting
Research Team
J
Jeppe Friborg, MD, PhD
CONTACT
A
Anne Lindegaard, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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