Actively Recruiting
Study of Different Therapeutic Strategies in Hydatidiform Mole With Lung Nodule
Led by Women's Hospital School Of Medicine Zhejiang University · Updated on 2026-03-16
30
Participants Needed
1
Research Sites
609 weeks
Total Duration
On this page
Sponsors
W
Women's Hospital School Of Medicine Zhejiang University
Lead Sponsor
Q
Qilu Hospital of Shandong University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of present study is to provide clinical evidences for the appropriate management of molar pregnancy with lung nodule. The hydatidiform mole patients with lung nodule ≥1.0cm will be randomized into 2 groups: A. treated with chemotherapy immediately, B. follow up until hCG level met FIGO diagnostic criteria of GTN (B1) or hCG level declined to normal spontaneously (B2). Lung nodule \<1.0cm will directly treated as group C
CONDITIONS
Official Title
Study of Different Therapeutic Strategies in Hydatidiform Mole With Lung Nodule
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pathologically confirmed hydatidiform mole
- Lung nodules detected by lung CT with possibility of metastasis
- hCG levels do not meet FIGO 2018 diagnostic criteria for gestational trophoblastic neoplasia
- Willingness to comply with study protocol and regular follow-up
- Signed informed consent form
You will not qualify if you...
- History of lung nodules
- Lung nodules caused by other diseases such as tuberculosis or pneumonia
- Prior prophylactic hysterectomy or chemotherapy
- Pathologically confirmed gestational trophoblastic neoplasia before or at enrollment
- Immunosuppressive diseases or use of immunosuppressants
- Participation in other clinical trials simultaneously
- Unable or unwilling to provide written informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Weiguo Lv
Hangzhou, Zhejiang, China
Actively Recruiting
Research Team
X
Xiao Li, dortor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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